Puas yog NMN Tsim Nyog Tau Txais?

"NMNyog ib qho txuj ci tseem ceeb, "hais tias ib lub ntsiab lus. "NMN tsuas yog cov zis kim xwb," hais tias lub rooj sib tham cynical post.Raws li ib tug neeg uas tau siv ntau xyoo embedded nyob rau hauv botanical extract thiab nutraceutical kev lag luam, kuv twb pom cov khoom xyaw tuaj thiab mus. Tab sis NMN (-Nicotinamide Mononucleotide) txawv. txiav- ntug Harvard kev tshawb fawb tau ntsib ntau -billion duas peev lag luam, tag nrho thaum dodging qhov tsis ntseeg ntawm cov neeg tswj hwm thoob ntiaj teb.

Yog li cia peb ua siab ncaj rau ib pliag. Txawm hais tias koj yog ib tus neeg xav paub txog kev tiv thaiv- kev laus, lossis tus tswv lag luam xav txog kev tshaj tawm cov khoom lag luam NMN, tej zaum koj yuav nug tib yam: NMN puas tsim nyog?

Ua ntej peb tham txog tus nqi, peb yuav tsum tham txog biology. NMN yog ib qho tshwm sim tshwm sim hauv cov khoom me me hauv cov khoom noj xws li avocados, zaub qhwv, thiab zaub qhwv. Tab sis koj yuav tsum tau noj txog 100kg ntawm broccoli kom tau txais cov tshuaj muaj feem cuam tshuam.

Hauv koj lub cev, NMN txoj haujlwm tseem ceeb yog ua tus thawj coj ncaj qha rau NAD + (Nicotinamide Adenine Dinucleotide). Xav txog NAD + raws li "lub zog txiaj" ntawm koj lub hlwb. Yog tsis muaj nws, koj mitochondria (cov nroj tsuag fais fab) kaw, koj DNA nres kho nws tus kheej, thiab koj lub hlwb tseem ceeb tsis nco qab yuav ua li cas.Qhov teeb meem? Raws li peb ntaus peb 40s thiab 50s, peb cov NAD + qib poob rau ze li ib nrab ntawm qhov lawv nyob hauv peb cov hluas [1]. Qhov kev poob qis no yog qhov cim ntawm kev laus. Los ntawm kev noj NMN, peb tseem ceeb "refueling" lub tank kom lub cellular machinery khiav.

Kuv feem ntau qhia peb cov neeg siv khoom: "Tsis txhob tso siab rau kev lag luam; tso siab rau cov phooj ywg-cov ntaub ntawv tshuaj xyuas."

1. Tsiaj Txhaum
NMN niaj hnub craze pib nrog Dr. David Sinclair txoj haujlwm ntawm Harvard Medical School. Hauv kev tshawb fawb txog keeb kwm, cov nas laus kho nrog NMN tau pom tias muaj kev txhim kho zoo kawg nkaus hauv kev kho DNA thiab cov leeg nqaij. Qhov tseeb, cov hlwb ntawm 22-hli- cov nas qub (qhov sib npaug ntawm 60- xyoo-} neeg laus) tau los ua qhov txawv ntawm cov nas hnub nyoog 6 hli (ib tug 20-xyoo-laus) tom qab tsuas yog ib lub lim tiam ntawm kev kho mob[2].

2. Tib neeg kev kho mob tiag tiag
"Ntaus tsis yog tib neeg," cov skeptics hais. Lawv hais yog lawm. Txawm li cas los xij, kev sim tib neeg tsis ntev los no tab tom sau qhov sib txawv:

Insulin rhiab heev:Ib txoj kev tshawb fawb xyoo 2021 tau tshaj tawm hauv Kev Tshawb Fawb tau pom tias NMN nce cov leeg nqaij insulin rhiab heev thiab qhia txog kev kho cov leeg nqaij hauv cov poj niam tom qab yug me nyuam nrog prediabetes[3].

Lub cev ua haujlwm:Ib qho randomized, ob npaug -qhov muag tsis pom, placebo- tswj kev tshawb fawb hauv 2022 nrog rau 80 tus neeg laus hauv nruab nrab- cov neeg laus pom tias NMN nce kev taug kev deb thiab txhim kho tag nrho cov qhab nia noj qab haus huv piv rau pawg placebo [4].

Aerobic muaj peev xwm:Kev tshawb fawb luam tawm nyob rau hauv Phau Ntawv Xov Xwm ntawm Lub Koom Haum Ntiaj Teb Kev Noj Qab Haus Huv Kev Noj Qab Haus Huv tau pom tias NMN supplementation ua rau kom lub qhov cua nkag mus rau hauv cov neeg ncaws pob ncaws pob, qhia tias nws pab cov leeg siv cov pa oxygen ntau dua. [5].

Yog tias koj yog tus thawj saib xyuas kev yuav khoom lossis tus kws tshaj lij kev lag luam, koj paub tias "kev ua tau zoo ntawm kev tshawb fawb" tsis yog ib txwm sib npaug "kev ua lag luam vam meej." Tab sis nrog NMN, qhov kev thov yog visceral.

1. Tus lej
Lub ntiaj teb no los tiv thaiv- kev lag luam kev laus yog kwv yees kom tshaj $ 420 nphom los ntawm 2030. Nyob rau hauv no, NAD+ boosters yog qhov ceev tshaj plaws - loj hlob sub- ntu. Peb tab tom pom kev hloov pauv loj hauv cov neeg siv khoom noj: tib neeg tsis xav tau "cov khoom noj khoom haus" (multivitamins); lawv xav tau "functional longevity."

2. Txoj Cai Tswjfwm Ntiag Tug
Kuv yuav tsum ua siab ncaj rau koj- thaj chaw tswj hwm yog me ntsis ntawm cov menyuam coaster.

Teb Chaws Asmeskas:FDA tsis ntev los no tau ua rau muaj kev ntxhov siab los ntawm hais tias NMN tsis tuaj yeem ua lag luam raws li kev noj haus ntxiv vim nws tau raug tshuaj xyuas raws li cov tshuaj tshiab. Txawm li cas los xij, kev tswj hwm tau tsom mus rau kev thov ntau dua li ntawm cov khoom xyaw nws tus kheej.

Nyiv:Nyiv tseem yog tus thawj coj, tau sau npe NMN raws li cov khoom noj khoom haus, uas tau txhawb nqa lub khw muag khoom loj nyob rau ntawd.

Tuam Tshoj:Thaum kev muag khoom hauv tsev tau raug tshuaj xyuas nruj, qhov kev thov los ntawm kev hla - ciam teb e- kev lag luam tseem nyob rau hnub qub.

Puas yog tshuaj ntsuab? Tsis muaj.

Qhov kev tsis sib haum xeeb feem ntau yog los ntawm kev lag luam nrov nrov. Vim tias NMN kim ​​los tsim, kev lag luam raug dej nyab nrog "fake" lossis "industrial-qib" NMN.

Qhov teeb meem Stability:Ntau NMN hmoov nyob rau hauv kev ua lag luam degrade nyob rau hauv lub hlis yog tsis muab cia rau hauv ib tug lab -qib freezer.

Qhov teeb meem Purity:Qee cov neeg muag khoom muag 80% purity NMN, tawm hauv 20% ntawm "tsis paub cov khoom lag luam" hauv koj cov tshuaj ntsiav.

Thaum tib neeg hais tias "NMN tsis ua haujlwm rau kuv," feem ntau yog vim lawv tsis noj NMN -lawv tau noj cov hmoov nplej dawb kim nrog cov kab ntawm NAD + cov khoom ua ntej.

Raws li tus neeg muag khoom, kuv feem ntau pom cov tswv lag luam ua yuam kev ntawm kev xaiv tus nqi qis tshaj. Hauv ntiaj teb NMN, tus nqi qis yog tus chij liab. Qhov "muaj nqis" ntawm NMN yog nyob ntawm peb yam:

• Purity (>= 99%): At Botanical Cube Inc., we utilize High-Performance Liquid Chromatography (HPLC) to ensure every batch is >= 99% ntshiab. Vim li cas qhov ntawd 1% tseem ceeb? Vim hais tias nyob rau hauv ib koob tshuaj 500mg, 1% ntawm impurities yog 5mg ntawm cov tshuaj tsis paub nkag mus rau hauv koj lub cev txhua hnub.

• Txheej txheem ntau lawm:Enzymatic vs. Chemical: Ntau qhov pheej yig dua NMNs yog tsim los ntawm cov tshuaj synthesis, uas tuaj yeem tawm tom qab hnyav hnyav residues. Peb siv Biological Enzyme Catalysis. Qhov no yog "ntsuab" thev naus laus zis uas ua raws li koj lub cev tsim cov tshuaj molecules. Nws muaj kev nyab xeeb thiab ruaj khov dua.
• Stability thiab Particle Science:We've engineered our NMN powder to have a high bulk density, making it perfect for capsule filling or tablet pressing without the need for excessive binders.

Yog tias koj tab tom nrhiav kev tshaj tawm lossis ua kom zoo dua los tiv thaiv - kab laus, koj tsis yog xav tau tus neeg muag khoom xwb; koj xav tau tus khub uas nkag siab txog kev tshawb fawb.

• Verified Specs:Peb muab tag nrho COA (Certificate of Analysis) thiab thib peb -lab kuaj rau txhua pawg.
• Kev Pabcuam Ua Raws Cai:Peb pab koj nrhiav cov ntaub ntawv xav tau rau kev lag luam thoob ntiaj teb (GMP, ISO, HALAL).
• Formulation Expertise:Peb pab koj nkag siab tias NMN cuam tshuam li cas nrog lwm cov khoom xyaw xws li Resveratrol lossis PQQ los tsim cov khoom "synergy" uas ua rau cov txiaj ntsig tau zoo.

Los ntawm kev pom kev tshawb fawb, NMN yog ib qho tseem ceeb tshaj plaws ntawm lub xyoo pua 21st. Cov ntaub ntawv hais txog kev kho DNA thiab kev noj qab haus huv mitochondrial yog qhov tseem ceeb heev uas yuav tsis quav ntsej.Los ntawm kev pom kev lag luam, NMN tsis yog "txoj kev" - nws tab tom dhau los ua lub hauv paus ntawm kev lag luam ntev. NMN yeej tsim nyog nws -tab sis tsuas yog tias qhov zoo tshaj qhov kev thuam. Hauv kev lag luam tsim los ntawm kev ntseeg siab, koj tsis tuaj yeem them taus rau kev cuam tshuam ntawm cov khoom siv raw. "NMN seb nws puas tsim nyog nws tsis yog nyob ntawm tus qauv, tab sis ntawm tus neeg muag khoom koj xaiv."

Tsis txhob khom rau "qib kev lag luam" thaum koj tuaj yeem muab koj cov neeg siv khoom siv tshuaj - qib purity. Txawm hais tias koj xav tau 1kg qauv rau R & D lossis 100kg rau kev tshaj tawm thoob ntiaj teb, kuv pab neeg thiab kuv nyob ntawm no los txhawb koj cov qauv tsim thiab cov saw hlau xav tau.Tau txais kev sib tham rau kev cai hais los yog COA daim ntawv qhia:sales@botanicalcube.com.

[1] Massudi, H., et al. (2012). "Lub hnub nyoog- cuam tshuam txog kev hloov pauv hauv oxidative kev nyuaj siab thiab NAD + metabolism hauv tib neeg cov ntaub so ntswg." PLoS ONE, 7(7), e42357. (Txoj kev tshawb fawb no lees paub qhov poob qis ntawm NAD + qib hauv tib neeg cov tawv nqaij thiab lub paj hlwb thaum peb muaj hnub nyoog).

[2] Gomes, AP, et al. (2013). "Kev txo qis NAD+ ua rau lub xeev pseudohypoxic cuam tshuam rau nuclear- mitochondrial kev sib txuas lus thaum lub sij hawm laus." Cell, 155(7), 1624-1638. (Qhov kev tshawb fawb Harvard pom tau tias NMN tuaj yeem thim rov qab mitochondrial aging hauv nas).

[3] Yoshino, M., et al. (2021). "Nicotinamide mononucleotide nce cov leeg nqaij insulin rhiab heev rau cov poj niam prediabetic." Science, 372(6547), 1224-1229. (Thawj qhov kev kuaj mob loj tshaj plaws uas qhia txog NMN txhim kho kev noj qab haus huv ntawm metabolic thiab insulin rhiab heev hauv tib neeg cov leeg pob txha).

[4] Yi, L., et al. (2023). "Kev ua tau zoo thiab kev nyab xeeb ntawm beta-nicotinamide mononucleotide (NMN) supplementation nyob rau hauv cov neeg laus noj qab nyob zoo- cov neeg laus: ib tug randomized, multicenter, ob - dig muag, placebo- tswj, parallel- pab pawg, koob tshuaj - nyob ntawm seb. GeroScience, 45(1), 29-43. (Ib qho kev sim tib neeg ua pov thawj NMN nce qib NAD + thiab txhim kho lub cev taug kev deb).

[5] Li, B., et al. (2021). "Nicotinamide mononucleotide supplementation pab txhawb kev muaj peev xwm aerobic hauv cov neeg nyiam ua si: kev sib tw, ob npaug - qhov muag tsis pom kev." Phau ntawv Journal of the International Society of Sports Nutrition, 18(1), 54. (Cov pov thawj kho mob uas qhia tias NMN txhim kho kev siv cov pa oxygen hauv tib neeg cov leeg thaum lub sij hawm qoj ib ce).