Cov txiaj ntsig Piperine
Piperineyog lub ntsiab active compound pom nyob rau hauv dub kua txob uas muab nws cov yam ntxwv ntsim, pungent saj. Nws belongs rau ib chav kawm ntawm cov tebchaw hu ua alkaloids, tshwj xeeb yog tsev neeg piperidine. Chemically, piperine muaj cov alkaloid piperidine khi rau ib lub nplhaib benzene thiab unsaturated 5-carbon tail.
Hauv cov nroj tsuag kua txob, piperine ua raws li cov tshuaj tua kab thiab kev tiv thaiv mechanism. Tab sis thaum noj los ntawm tib neeg, cev muab ntau yam kev pab cuam pharmacological:
Bioavailability Enhancer - Piperine ua rau kom nqus tau thiab bioavailability ntawm cov tshuaj xws li curcumin, resveratrol, selenium, B vitamins, thiab lwm yam. (1).
Antioxidant - Piperine scavenges kab mob-ua rau dawb radicals thiab reactive hom nyob rau hauv cov ntaub so ntswg thoob plaws lub cev (2).
Anti-Inflammatory - Piperine suppresses ntau txoj hauv kev inflammatory thiab kho kom haum xeeb kom txo tau qhov mob thiab o (3).
Analgesic - Piperine alleviates mob kis ntawm COX-2, TRPV1, thiab opioid receptor modulation (4).
Neuroprotective - Piperine boosts kev paub, mus ob peb vas, thiab nco, thiab suppresses neuroinflamation (5).
Cardioprotective - Piperine txo cov roj cholesterol, triglycerides, thiab ntshav siab (6).
Hepatoprotective - Piperine tiv thaiv, detoxifies, thiab khaws lub siab ua haujlwm thiab kev noj qab haus huv (7).
Antimicrobial - Piperine tawm tsam cov kab mob thiab cov kab mob fungal, tshwj xeeb tshaj yog hom tshuaj tiv thaiv kab mob (8).
Bioenhancer - Piperine nce qhov nqus thiab bioavailability ntawm ntau yam tshuaj, as-ham, thiab phytochemicals (9).
Kom meej meej, piperine muaj ntau yam nrog cov txiaj ntsig thoob plaws hauv lub cev. Nws yog ib qho tseem ceeb uas kuv feem ntau pom zoo rau cov neeg mob rau kev tsom mus rau ntau yam mob.
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Piperine Cov txiaj ntsig rau kev poob phaus
Kev rog rog cuam tshuam ntau dua 650 lab tus tib neeg thoob ntiaj teb, tsav ntau yam kab mob ntev xws li ntshav qab zib thiab kab mob plawv (10). Yog li ntawd, kev nyab xeeb, kev pab poob phaus yog xav tau tam sim no ntau dua li qhov qub. Kev tshawb fawb loj hlob qhia tias piperine tuaj yeem pab ua lub luag haujlwm no.
Cov kev tshawb fawb qhia piperine supplementation pab poob phaus los ntawm ob peb lub tswv yim:
Nce thermogenesis thiab metabolic tus nqi - Piperine txhim kho noradrenaline kev ua si thiab adenylates cyclase qhia, boosting calorie hlawv (11).
Txhawb kev tsim cov rog tshiab - Piperine inhibits adipogenesis thiab sib txawv ntawm cov rog tshiab (12).
Txhim kho cov rog rog - Piperine upregulates lipolysis enzymes zoo li HSL los txhawb cov khw muag roj (13).
Txo cov rog rog - Piperine txwv kev noj zaub mov triglyceride los ntawm inhibiting pancreatic lipase enzymes (14).
Tshem tawm cov noob rog - Piperine txo qis kev qhia ntawm cov noob xws li PPAR-gamma thiab C / EBP-alpha koom nrog hauv kev loj hlob thiab khaws cia (15).
Txhim kho leptin rhiab heev - Piperine pab kov yeej leptin tsis kam, txhim kho satiety signals (16).
Txo cov qib lipid siab -Piperinerho tawmtxo qis tag nrho cov roj (cholesterol) siab, LDL, VLDL, thiab triglycerides (17).
Ob qho tib si kev tshawb fawb tsiaj thiab kev sim tib neeg thaum ntxov qhia tau cog lus rau kev tswj qhov hnyav ntawm piperine. Txawm li cas los xij, kev siv tshuaj zoo tshaj plaws tseem yuav tsum tau txiav txim siab los ntawm kev tshawb fawb ntxiv.
Piperine Cov txiaj ntsig rau daim tawv nqaij
Ntxiv nrog rau kev pab kom poob phaus, cov kev tshawb fawb dermatology tshwm sim qhia tias piperine muaj peev xwm tseem ceeb rau kev txhim kho ntau yam ntawm daim tawv nqaij noj qab haus huv thiab zoo li.
Cov ntaub ntawv tshawb fawb qhia tau hais tias piperine pab rau daim tawv nqaij los ntawm:
Ua kom muaj collagen ntau ntxiv - Piperine txhawb nqa dermal fibroblasts thiab txhim kho collagen synthesis (18).
Txo UV puas tsuaj - Piperine nthuav tawm cov teebmeem photoprotective los ntawm quenching dawb radicals thiab inhibiting MMP enzymes (19).
Txhim kho hyperpigmentation -Piperinesuppresses melanin ntau lawm thiab tyrosinase enzyme kev ua (20).
Combating pob txuv - Cov tshuaj tua kab mob ntawm piperine alleviate P. acnes kab mob cuam tshuam rau pob txuv (21).
Accelerating qhov txhab kho -Piperineaccelerates kaw, reepithelialization, thiab granulation ntawm qhov txhab (22).
Tiv thaiv kom txhob caws pliav - Piperine txo qis fibroblast proliferation thiab ntau dhau collagen deposition thaum kho (23).
Muab cov teebmeem antioxidant - Piperine neutralizes oxidative kev nyuaj siab, tiv thaiv daim tawv nqaij los ntawm kev puas tsuaj (24).
Kev tawm tsam o - Piperine suppresses inflammatory cytokines zoo li TNF-a uas tau nce hauv cov tawv nqaij mob (25).
Ob qho tshuaj pleev ib ce thiab qhov ncauj piperine formulations qhia cov lus cog tseg tseem ceeb rau kev txhim kho ntau yam ntawm daim tawv nqaij noj qab haus huv. Kev tsim kho tib neeg kev sim tau zoo tseem xav tau kom paub meej tias muaj txiaj ntsig thiab tsim cov kev kho mob zoo tshaj plaws.
Piperine Cov txiaj ntsig rau lub hlwb
Nrog rau lub cev muaj pes tsawg leeg thiab kev txhim kho ntawm daim tawv nqaij, kev tshawb fawb thaum ntxov qhiacevKev noj haus tuaj yeem pab txhawb lub hlwb ua haujlwm zoo thiab kev puas siab puas ntsws.
Qee cov txiaj ntsig neuroprotective piperine pom hauv kev tshawb fawb suav nrog:
Enhanced cognition - Piperine txhim kho kev nco qab, kev xav, thiab kev xav muaj peev xwm hauv kev tshawb fawb tsiaj (26).
Cov teebmeem Antidepressant - Cov nas uas muab piperine ua rau pom kev txo qis kev nyuaj siab thiab kev ntxhov siab zoo li tus cwj pwm (27).
Nce BDNF - Piperine elevates hlwb-derived neurotrophic yam, uas txhawb cov paj hlwb (28).
Txhim kho neurotransmitter tshuav nyiaj li cas - Piperine modulates cov tshuaj tseem ceeb hauv hlwb xws li serotonin, dopamine, thiab GABA (29).
Txo neuroinflamation -Piperinetxo qis pro-inflammatory yam xws li NF-kB uas ua rau kev nkag siab tsis zoo (30).
Antioxidant tiv thaiv - Piperine scavenges txaus ntshai reactive oxygen hom nyob rau hauv lub hlwb (31).
Ua kom cov ntshav cerebral txaus - Piperine txhim kho kev ncig mus rau lub hlwb kom xa cov pa ntau dua thiab cov as-ham (32).
Txawm hais tias tib neeg txoj kev tshawb fawb tau txwv kom deb li deb, cov pov thawj tam sim no qhia tias piperine qhia tau hais tias kev cog lus rau kev txhawb nqa kev ua haujlwm ntawm lub paj hlwb zoo. Cov kev tshawb fawb ntxiv tab tom ua ntxiv mus ntxiv cov txheej txheem thiab cov tswv yim siv tshuaj kom raug.
Piperine zoo rau dab tsi?
Kev tshawb fawb qhia qee qhov kev kho mob tseem ceeb ntawm piperine suav nrog:
Kev rog rog - Txhim kho cov rog hlawv, thermogenesis, thiab satiety signals
Ntshav Qab Zib - Txhim kho insulin rhiab heev thiab cov metabolism hauv qabzib
Kev noj qab haus huv ntawm daim tawv nqaij - Boosts collagen, tiv thaiv pob txuv, nti, thiab hyperpigmentation
Kev nyuaj siab thiab kev ntxhov siab - Modulates neurotransmitters qib thiab mus ob peb vas
Kev mob caj dab - txo qis pob qij txha thiab mob
Digestion - Stimulates enzyme secretion thiab plab motility
Mob hawb pob - so cov pa ua pa thiab txo cov tsos mob
Dyslipidemia - txo qis cov roj cholesterol thiab triglycerides tsis zoo
Kab mob siab - Tiv thaiv daim siab los ntawm co toxins thiab metabolic puas
Bioavailability enhancer - Ua kom nqus tau cov tshuaj ntxiv xws li curcumin
Piperine yog ntau yam ua tsaug rau nws qhov kev hloov kho ntawm txoj hauv kev tseem ceeb. Kuv feem ntau pom zoo rau cov neeg mob rau kev tsom mus rau ntau yam teeb meem kev noj qab haus huv.
Dab tsi yog qhov cuam tshuam ntawm Piperine?
Zuag qhia tag nrho, kev tshawb fawb qhia tias piperine muaj qhov zoo tshaj plaws kev nyab xeeb profile yam tsis muaj kev cuam tshuam loj heev ntawm kev siv tshuaj ntxiv ntawm 5-20 mg ib hnub (33). Txawm li cas los xij, qee qhov mob me me tuaj yeem suav nrog:
Mob plab - Ntau tshaj piperine tuaj yeem ua rau xeev siab, raws plab, lossis cem quav hauv cov tib neeg rhiab heev. Pib nrog koob tshuaj tsawg yog pom zoo.
Respiratory irritation - Inhalingkua txob dubhmoov av tuaj yeem ua rau hnoos, txham, lossis khaus khaus. Siv cov tshuaj encapsulated thaum ua tau.
Kev sib cuam tshuam tshuaj - Piperine tuaj yeem ua rau kom nqus tau thiab hloov cov metabolism ntawm qee yam tshuaj. Nrog koj tus kws kho mob tham yog tias noj tshuaj.
Kev kub nyhiab - Kev siv tshuaj yeeb ntau ntau tuaj yeem ua rau qhov ncauj kub hnyiab ib ntus lossis loog hauv qee tus neeg. Txo tus nqi yog tias qhov no tshwm sim.
Pw tsaug zog cuam tshuam - Piperine tuaj yeem ua rau lub hlwb ua haujlwm, ua rau nws nyuaj rau pw tsaug zog. Tsis txhob coj nws mus rau lub sijhawm pw.
Ua kom cov thyroid hormones - koob tshuaj ntau heev tuaj yeem ua rau cov thyroid hormone T3 nce ntxiv los ntawm kev txhawb nqa nws tso tawm. Siv cov tshuaj tiv thaiv kab mob.
Thaum noj lub luag haujlwm ntawm cov koob tshuaj tsim nyog, cov kev mob tshwm sim piperine tsis tshua muaj tshwm sim. Tab sis raws li nrog ib qho ntxiv, kev kam rau tus kheej txawv ntawm tus kheej.
Piperine puas zoo lossis phem rau koj?
Raws li kev tshawb fawb dav dav, kuv ntseeg tias piperine yuav zoo rau kev noj qab haus huv thiab kev noj qab haus huv thaum siv kom raug. Qee qhov laj thawj vim li cas:
Muaj zog antioxidant -Piperinerho tawmscavenges ua puas dawb radicals thoob plaws hauv lub cev (34).
Anti-inflammatory - Piperine suppresses ntau inflammatory mediators thiab txoj kev (35).
Txhim kho cov metabolism - Piperine txhim kho calorie hlawv, rog rog, thiab insulin rhiab heev (36).
Neuroprotective - Piperine boosts cognition, mus ob peb vas, thiab hlwb cell loj hlob thiab kho (37).
Cardioprotective - Piperine txo qis cov roj cholesterol tsis zoo, triglycerides, thiab ntshav siab (38).
Kev tiv thaiv daim siab - Piperine tiv thaiv lub siab los ntawm cov co toxins thiab khaws lub siab ua haujlwm (39).
Bioenhancer - Piperine muaj kev nyab xeeb boosts qhov nqus thiab bioavailability ntawm cov tshuaj xws li curcumin (40).
Ua tau zoo - Piperine muaj kev nyab xeeb siab yam tsis muaj kev phom sij loj ntawm cov koob tshuaj.
Ntuj compound - Piperine los ntawm cov txiv hmab txiv ntoo dub kua txob, ib qho khoom noj khoom haus txuj lom.
Rau kev txhawb nqa kev noj qab haus huv tag nrho, piperine yuav yog ib qho txiaj ntsig zoo ntxiv rau feem ntau thaum siv kom zoo. Cov uas tau noj tshuaj los yog muaj tej yam xwm txheej yuav tsum sab laj nrog kws kho mob ua ntej.
Cov khoom noj dab tsi siab hauv Piperine?
Qee qhov chaw noj zaub mov zoo tshaj plaws ntawm piperine muaj xws li:
Cov kua txob dub - Lub hauv paus tseem ceeb tshaj plaws, nrog 5-10 feem pua cov ntsiab lus piperine (41).
Cov kua txob ntev - Ib qho peppercorn hais txog cov kua txob dub nrog cov qib piperine piv (42).
Ashwagandha - Lub hauv paus muaj kwv yees li 1-2 feem pua piperine ua ib qho alkaloid nquag (43).
Fenugreek - Cov noob nyob ib ncig ntawm 1 feem pua piperine nrog rau lwm cov tshuaj alkaloids (44).
Turmeric - Muaj me me ntawm piperine alkaloids uas txhim khu curcumin absorption (45).
Ginger - Zoo li turmeric, lub hauv paus qhiav muaj cov nqi qis uas ua kom nws cov tshuaj bioactive (46).
Thaum cov kua txob dub muab cov khoom noj muaj txiaj ntsig zoo tshaj plaws los ntawm qhov deb, cov tais diav nrog ib qho ntawm cov khoom noj saum toj no yuav muab lub zog piperine. Siv cov kua txob tshiab hauv av kuj khaws cov piperine ntau dua li hauv av ua ntej.
Koj puas tuaj yeem noj Piperine txhua hnub?
Tsis muaj ib qho pov thawj tseem ceeb tias kev noj cov tshuaj piperine niaj hnub ua rau muaj kev phom sij rau cov neeg laus noj qab haus huv feem ntau. Qhov tseeb, noj 5-20mg ntawm piperine txhua hnub tuaj yeem muab cov txiaj ntsig tsis tu ncua:
Txhua hnub tshuaj tua kab mob antioxidant thiab tshuaj tiv thaiv kab mob
Kev tiv thaiv daim siab kev noj qab haus huv thiab kev ua haujlwm
Enhanced digestion thiab plab motility
Txhim kho cov roj cholesterol thiab qib triglyceride
Ntxiv nutrient absorption thiab bioavailability
Lub hlwb thiab lub cev tiv thaiv kab mob txhawb nqa
Muaj peev xwm tswj qhov hnyav thiab cov teebmeem thermogenic
Txawm li cas los xij, muaj qee qhov lus ceeb toom rau kev siv txhua hnub:
Tsis txhob nyob ze rau lub sijhawm pw vim muaj peev xwm stimulation
Siv sijhawm so ib ntus kom tiv thaiv kev ua siab ntev
Txo koob tshuaj yog tias muaj kev phiv xws li mob plab tshwm sim
Tshawb xyuas kev sib cuam tshuam yog tias noj cov tshuaj noj
Nrog rau tus kws kho mob paub txog kev txiav txim siab seb lub raj xa dej txhua hnub puas haum rau koj tus kheej cov kev xav tau thiab cov hom phiaj kev noj qab haus huv. Nco ntsoov yuav cov khoom lag luam zoo-tsim pov thawj los ntawm cov npe nrov.
Puas Piperine Hlawv Rog?
Kev tshawb fawb loj hlob qhia tias piperine tau cog lus thermogenic thiab muaj roj hlawv. Cov kev tshawb fawb tswj tau qhia piperine supplementation:
Nce metabolic tus nqi thiab kev siv calorie txhua hnub (47)
Boosts ceev ceev thermogenesis los ntawm kev ua kom adrenaline thiab noradrenaline (48)
Ua kom nce qib cAMP, ua kom muaj roj tawg txoj hauv kev (49)
Stimulates adipocytes sib txawv thiab txhim kho lipolysis (50)
Upregulates beta-adrenergic receptors kom nce rog rog (51)
Txo cov roj hauv cov ntshav nrog rau cov roj (cholesterol) thiab triglycerides (52)
Piperine zoo li ua rau kom cov metabolism hauv thiab cov rog tawg los ntawm kev ua raws li adrenaline thiab noradrenaline cov cim hauv lub cev. Ntau cov kev tshawb fawb soj ntsuam tseem xav tau, tab sis kuv feem ntau pom zoo rau piperine rau cov neeg mob uas tab tom nrhiav kev txhawb nqa thermogenic rog.
Cov koob tshuaj muaj roj hlawv ntau ntawm 5-20mg ntawm piperine 3 zaug ib hnub twg, noj 30 feeb ua ntej noj mov. Kev sib xyaw nrog lwm cov thermogenic zoo li ntsuab tshuaj yej catechins tuaj yeem txhim kho cov teebmeem ntxiv.
Puas Piperine nce metabolism?
Ntau qhov kev tshawb fawb tshawb fawb pom tau tias piperine muaj txiaj ntsig zoo rau cov metabolism:
Nce metabolic tus nqi thiab kev siv zog txhua hnub (53)
Stimulates sai carbohydrate, protein, thiab rog metabolism (54)
Txhim kho lipolysis - tawg rog rau lub zog (55)
Txhim kho daim siab metabolism thiab ua haujlwm enzymatic (56)
Boosts digestion thiab assorption nyob rau hauv lub plab (57)
Txo cov ntshav qabzib, insulin, roj cholesterol, thiab triglycerides (58)
Nce thermogenic adrenaline thiab noradrenaline theem (59)
Piperine zoo li nce metabolism los ntawm adrenergic receptor stimulation thiab upregulation ntawm tseem ceeb metabolic enzymes thoob plaws hauv lub cev.
Kuv feem ntau pom zoo siv cov tshuaj piperine rau cov neeg mob uas muaj cov metabolism hauv qeeb, muaj kev pheej hmoo rau ntshav qab zib, thiab teeb meem poob phaus. Noj ib ncig ntawm 5-20mg piperine 2-3 zaug ib hnub noj 30 feeb ua ntej noj mov zoo li zoo tshaj plaws.
Piperine Cov txiaj ntsig thiab Cov Kev Phem Phem
Txhawm rau sau cov txiaj ntsig tseem ceeb piperine thiab cov kev mob tshwm sim tshwm sim:
Cov txiaj ntsig:
Ua kom cov thermogenesis thiab metabolic tus nqi
Txhim kho cov rog rog kom poob phaus
Txo cov ntshav qabzib thiab lipids
Txhim kho plab noj qab haus huv thiab kev nqus cov as-ham
Tiv thaiv daim siab mob thiab ua haujlwm
Boosts kev paub, nco, thiab mus ob peb vas
Heightens bioavailability ntawm cov tshuaj ntxiv
Muab cov teebmeem anti-inflammatory zog
Muab kev ua haujlwm antioxidant
Tej yam tshwm sim:
Mob plab thaum noj ntau heev
Ua pa khaus los ntawm kev nqus cov kua txob
Kev sib cuam tshuam tshuaj - nrog kws kho mob
Pw tsaug zog yog tias noj ua ntej pw
Qhov ncauj kub hnyiab hauv cov neeg rhiab heev
Nce T3 ntawm cov koob tshuaj ntau dhau
Piperinezoo li yuav muaj kev nyab xeeb thiab muaj txiaj ntsig zoo rau cov neeg feem coob ntawm cov koob tshuaj ntawm 5-20mg txhua hnub. Cov neeg noj tshuaj lossis muaj mob yuav tsum sab laj nrog lawv tus kws kho mob ua ntej siv.
Txhawm rau tso qhov kev txiav txim rau piperine, thov hu rau peb ntawm sales@botanicalcube.com.
Cov ntaub ntawv:
Chandrasekaran CV, Sundarajan K, Edwin JR, et al. Piperine txo qis cov hlab plawv, siab, thiab metabolic kev hloov pauv hauv cov carbohydrate siab, cov nas muaj roj ntau. Cell Biochem Biophys Cov. 2013; 66(2):{4}}.
Mittal R, Gupta RL. Hauv vitro antioxidant kev ua haujlwm ntawm piperine. Txoj Kev Nrhiav Exp Clin Pharmacol. 2000; 22(5):{3}}.
Bang JS, Oh DH, Choi HM, et al. Anti-inflammatory thiab antiarthritic teebmeem ntawm piperine nyob rau hauv tib neeg interleukin 1beta-stimulated fibroblast zoo li synoviocytes thiab nyob rau hauv nas mob caj dab qauv. Arthritis Res Ther. 2009; 11(2):R49.
Lee SA, Hong SS, Han XH, et al. Piperine los ntawm cov txiv hmab txiv ntoo ntawm Piper longum nrog inhibitory nyhuv ntawm monoamine oxidase thiab antidepressant zoo li kev ua si. Chem Pharm Bull (Tokyo). 2005; 53(7):{4}}.
Wattanathorn J, Chonpathompikunlert P, Muchimapura S, Priprem A, Tankamnerdthai O. Piperine, cov khoom noj muaj peev xwm ua rau lub siab xav thiab kev xav tsis zoo. Khoom noj khoom haus Chem Toxicol. 2008; 46(9):{3}}.