Boswellia serrata, tseem hu ua Indian frankincense los yog Salai guggal, yog ib tsob ntoo nyob rau hauv Is Nrias teb uas tsim cov resin muaj cov tshuaj nquag hu ua boswellic acids. Extracts ua los ntawm cov resin no tau siv rau ib-paus xyoo nyob rau hauv Indian Ayurvedic tshuaj rau lawv anti-inflammatory, anti-arthritic, thiab analgesic zog. Hnub no,boswellia serrata extractyog loj hlob nyob rau hauv muaj koob meej raws li tej yam ntuj tso tshuaj pab txhawb kev noj qab haus huv o teb, hlwb ua hauj lwm, thiab ntau dua.
Nkag siab Boswellia Serrata Extract
Boswellia Serrata yog tsob ntoo nruab nrab mus rau loj ceg ntoo pom nyob rau hauv cov roob qhuav ntawm Is Nrias teb, Northern Africa, thiab Middle East. Tsob ntoo tsim cov pos hniav uas oozes tawm ntawm incisions ua nyob rau hauv bark. Cov resin no yog tom qab ntawd tau sau thiab ua kom huv los tsim cov ntsiab lus boswellia serrata extracts uas muaj cov khoom xyaw tseem ceeb, boswellic acids. Cov haib pentacyclic triterpene acids yog suav tias yog lub hauv paus ntawm boswellia cov kev pab kho mob.
Ntxiv nrog rau boswellic acids, boswellia extracts muaj lwm cov txiaj ntsig zoo xws li polysaccharides, roj tsis hloov pauv, thiab flavonoids. Kev sib xyaw ntawm cov phytochemicals ntuj no muab boswellia nws lub zog tiv thaiv kab mob, antioxidant, thiab tiv thaiv kab mob. Los ntawm inhibiting pro-inflammatory enzymes xws li 5-LOX thiab tswj lub cev tiv thaiv kab mob, boswellia extracts yuav pab kho lub hauv paus ua rau tom qab mob xws li mob caj dab, mob hawb pob, mob plab hnyuv, thiab ntau dua.
1 Qhov tseem ceeb ntawm Boswellia Serrata hauv Kev Txhawb Kev Noj Qab Haus Huv
Nrog rau mob o tam sim no txuas nrog ze li txhua yam kab mob loj, nrhiav kev nyab xeeb thiab muaj txiaj ntsig zoo los tswj cov lus teb inflammatory yog qhov tseem ceeb rau kev txhim kho tag nrho kev noj qab haus huv thiab kev noj qab haus huv. Boswellia serrata extracts qhia cov lus cog tseg tshwj xeeb hauv qhov no. Kev coj noj coj ua Ayurvedic tau tso siab rau cov khoom siv no los txhawb cov pob qij txha noj qab haus huv, ncig, plab zom mov, thiab ua pa rau ntau txhiab xyoo. Tam sim no kev tshawb fawb niaj hnub no tau lees paub qhov muaj zog tiv thaiv kab mob thiab tiv thaiv lub peev xwm ntawm boswellia ib yam nkaus. Kev noj zaub mov tsis tu ncua tuaj yeem pab tswj kom muaj qhov sib npaug ntawm qhov tsim nyog thiab mob ntau dhau rau kev noj qab haus huv zoo.
2 Cov khoom xyaw nquag hauv Boswellia Serrata Extract
Raws li tau hais, cov khoom xyaw tseem ceeb hauv boswellia ntseeg tias yog lub luag haujlwm rau nws cov teebmeem kev kho mob yog pentacyclic triterpenic acids, feem ntau:
Boswellic Acids:
- 11-keto- -boswellic acid (KBA)
- Acetyl- -boswellic acid
- Acetyl- -boswellic acid
Cov boswellic acids no tau pom nyob rau hauv kev tshawb fawb los inhibit pro-inflammatory enzymes xws li 5-lipoxygenase (5-LOX). Los ntawm kev ua li ntawd, lawv pab tswj kev tsim cov kab mob leukotrienes txuas nrog cov mob xws li mob caj dab, mob hawb pob, thiab mob plab hnyuv. Boswellic acids kuj tseem tuaj yeem pab txhawb kev noj qab haus huv ntawm cov ntshav mus rau cov pob qij txha, hlwb, thiab lwm yam ntaub so ntswg los ntawm kev tiv thaiv platelet aggregation thiab txhawb vasodilation.
3 Lwm yam Bioactive Compounds:
- Flavonoids - Muab kev txhawb nqa antioxidant
- Cov roj tseem ceeb - Pab txhawb kev tiv thaiv kab mob, tshuaj tiv thaiv kab mob, thiab cov txiaj ntsig analgesic
- Polysaccharides - Hloov kho lub cev tiv thaiv kab mob
Ua ke nrog boswellic acids, cov tshuaj no muabboswellia serrata extractnws muaj peev xwm tiv thaiv. Cov concentrations thiab potencies nyob ntawm qhov zoo ntawm cov txheej txheem extraction. Cov txheej txheem Ayurvedic tsoos suav nrog lub sijhawm kub kub, lim dej, thiab cov txheej txheem distillation tsim los khaws cov kua qaub tsis muaj zog thiab txhim kho kev ua kom zoo dua qub piv rau cov txheej txheem hnyav niaj hnub no.
1 Mechanisms of Action nyob rau hauv lub cev
Thaum noj, boswellia serrata cov khoom xyaw bioactive taug kev los ntawm cov hlab ntsha uas nthuav tawm cov kab mob tiv thaiv kab mob, tshuaj tua kab mob, thiab kev tswj hwm ntawm qib molecular. Hauv cov hlwb, boswellic acids inhibit qhov tsim thiab tso tawm ntau cov tshuaj tiv thaiv kab mob xws li leukotrienes, prostaglandins, interleukins, thiab TNF-alpha. Lawv kuj tseem tuaj yeem cuam tshuam cov noob qhia txog kev mob thiab kev tiv thaiv kab mob. Sab nraum cov hlwb, boswellia pab cov nqaij mos noj qab haus huv los ntawm kev txhawb nqa cov ntshav txaus los ntawm nws cov teebmeem ntawm vascular endothelium thiab platelets. Cov txheej txheem multimodal no ua rau boswellic acids muaj txiaj ntsig rau kev daws teeb meem mob ntev.
2 Pom zoo noj
Tam sim no tsis muaj cov lus qhia txog kev noj tshuaj rau boswellia. Feem ntau cov kev tshawb fawb qhia pom cov txiaj ntsig kho mob siv koob tshuaj ntawm 200-400mg ntawm boswellia serrata extract txhua hnub, qee zaum muab faib ua ntau yam. Cov ntawv ntsiav tshuaj thiab cov ntsiav tshuaj muaj ntau. Thaum siv cov resin nws tus kheej koob tshuaj txog li 1 gram ib hnub twg yuav tsum tau vim yog txo qis bioavailability piv rau cov extracts. Nco ntsoov ua raws li cov neeg tsim khoom pom zoo, tshwj xeeb tshaj yog thaum sib txuas nrog lwm cov tshuaj.
Qhov ntau npaum li cas yuav tsum tau ua kom haum rau tus neeg raws li lub cev hnyav, tus mob raug kho, thiab lwm yam tshuaj / botanicals uas lawv sib txuas nrog. Thaum feem ntau ua tau zoo, muaj ib txwm muaj peev xwm rau kev sib cuam tshuam nrog lwm cov tshuaj metabolized los ntawm daim siab. Cov neeg uas muaj cov tshuaj tiv thaiv coagulants, tshuaj tiv thaiv kab mob, lossis cov kws khomob yuav tsum tau ceev faj tshwj xeeb thiab sab laj nrog lawv tus kws kho mob ua ntej pib cov tshuaj ntxiv.
Cov txiaj ntsig kev noj qab haus huv ntawm Boswellia Serrata Extract
Nrog nws cov muaj zog sib xyaw ntawm cov kua qaub, roj, thiab cov as-ham,boswellia serrata extractmuaj ntau yam kev pab kho mob:
Anti-Inflammatory Properties
1 Txo kev mob pob qij txha thiab mob
Cov tshuaj tiv thaiv kab mob ntawm boswellic acids tau pom cov lus cog tseg tshwj xeeb hauv kev tshawb fawb ntawm cov ntaub ntawv ntawm kev mob caj dab vim yog mob ntev. Los ntawm inhibiting pro-inflammatory 5-LOX enzymes thiab tswj leukotrienes, boswellia extracts tau pom los txo qhov mob thiab kev puas tsuaj hauv pob qij txha vim mob rheumatoid mob caj dab thiab osteoarthritis. Qhov no ua rau muaj kev txhim kho tseem ceeb hauv kev sib koom tes, txhav, thiab kev txav mus los. Cov kev tshawb fawb sib piv kuj qhia tau hais tias muaj txiaj ntsig zoo sib xws thiab kev nyab xeeb rau cov kev kho mob NSAID ib txwm muaj tsawg dua cov kev mob tshwm sim.
Muaj peev xwm ua Ntuj Kev Kho Mob rau Kab Mob Kab Mob
Ntxiv nrog rau kev mob caj dab, kev tshawb fawb thaum ntxov qhia tias boswellia tuaj yeem cog lus tias yog lwm txoj kev kho mob rau lwm yam kab mob xws li mob hawb pob, mob plab hnyuv, kab mob hauv lub paj hlwb, thiab txawm tias qee yam ntawm daim tawv nqaij xws li psoriasis thiab eczema los ntawm kev txo cov leukotriene-mediated o, txhawb cov ntshav khiav, thiab stabilizing mast cells. Cov koob tshuaj Standardized nruab nrab ntawm 200-400mg tshwm sim zoo tshaj plaws raws li kev tshawb fawb soj ntsuam txog tam sim no.
2 Kev Txhawb Kev Tiv Thaiv
Qhov cuam tshuam rau kev tiv thaiv kab mob thiab Cytokine Production
Tshaj li cov kev cai o, boswellia extracts kuj muaj cov khoom siv immunomodulatory. Los ntawm kev cuam tshuam cov khoom ntim ntim cov qauv hauv spleen lymphocytes thiab cytokine ntau lawm, boswellic acids tuaj yeem kho lub cev tiv thaiv kab mob. Qhov no pab tswj cov kev cuam tshuam rau sab nraud hem los ntawm cov kab mob, irritants, thiab cell dysfunction ua rau muaj kev tiv thaiv kev tiv thaiv es tsis tswj qhov mob.
3 Muaj peev xwm siv tau los tiv thaiv kab mob
Los ntawm cov kev tiv thaiv kab mob no, kev tshawb fawb ntawm tes thiab tsiaj thaum ntxov qhia tau hais tias kev siv tshuaj tiv thaiv nrog boswellia serrata tuaj yeem pab tiv thaiv qee yam kab mob thiab kab mob xws li mob ntsws, mob meningitis, gonorrhea, herpes, thiab kab mob siab. Kev tshawb fawb ntxiv tseem xav tau kom paub meej tias kev tiv thaiv kev ua tau zoo ntawm tib neeg.
4 Lub hlwb noj qab haus huv thiab kev txawj ntse muaj nuj nqi
Cov teebmeem ntawm Cerebral Blood Flow thiab Neuroprotection
Kev tsis zoo, kev puas tsuaj oxidative, neuroinflammation thiab neurodegeneration dag nyob rau hauv lub hauv paus ntawm ntau yam kev txawj ntse los ntawm dementia mus rau kev nyuaj siab. Boswellic acids 'muaj peev xwm los txhawb cov ntshav cerebral thiab tiv thaiv cov ntaub so ntswg neural los ntawm cov tshuaj tua kab mob antioxidant thiab cov tshuaj tiv thaiv kab mob qhia tau hais tias muaj txiaj ntsig zoo rau kev noj qab haus huv thiab kev paub. Cov kev tshawb fawb tsiaj tau lees paub txog boswellia cov teebmeem neuroprotective uas ua rau muaj kev txhim kho kev kawm, nco khaws cia, thiab kev tswj kom zoo. Kev tshawb fawb tib neeg thaum ntxov kuj qhia tau tias txo kev ntxhov siab thiab kev txhim kho hauv kev xav hauv tsawg li 30 hnub thaum ntxiv nrog boswellia.
5 Muaj peev xwm siv tau los txhim kho kev nco thiab kev xav
Nrog rau ntau yam cuam tshuam nrog kev paub txog hnub nyoog poob qis, boswellia kev sib xyaw ua ke ntawm cov hlab ntshav, tiv thaiv kab mob, thiab cov txiaj ntsig antioxidant ua rau nws muaj peev xwm kho tau zoo. Kev tshawb fawb ntxiv tseem xav tau, tab sis cov txiaj ntsig ntawm cov paj hlwb ua ntej no kuj tseem qiv rau kev coj ua Ayurvedic ib txwm siv boswellia los txhawb kev xav, nco, thiab mus ob peb vas.
Cov kev phiv thiab kev ceev faj
Boswellia feem ntau tau txais txiaj ntsig zoo los ntawm cov neeg laus noj qab haus huv ntawm cov koob tshuaj pom zoo raws li nws cov keeb kwm ntev ntawm kev siv tshuaj Ayurvedic thiab kev tshawb pom tsis ntev los no. Txawm li cas los xij, qee qhov kev ceev faj tau lees paub:
Tej yam tshwm sim muaj xws li digestive teeb meem, xeev siab, kua qaub reflux/heartburn, tsam plab, raws plab los yog cem quav thaum noj qhov ncauj. Siv cov tshuaj pleev ib ce thaum kho cov mob hauv zos kom tsis txhob muaj cov tshuaj tiv thaiv kab mob. Pib nrog cov koob tshuaj qis tshaj plaws.
Tsis txhob thaum cev xeeb tub lossis pub niam mis tshwj tsis yog ua haujlwm nrog tus kws kho mob vim tsis muaj kev tshawb fawb txog kev nyab xeeb. Tej zaum yuav ua rau kev coj khaub ncaws ntau ntxiv.
Kev ceeb toom ceeb toom rau leej twg ntawm cov tshuaj tiv thaiv kab mob los yog tshuaj tiv thaiv coagulant los yog muaj cov kab mob los ntshav vim boswellia tuaj yeem ua rau cov ntshav txhaws qeeb. Tsis txhob noj tsawg kawg 2 lub lis piam ua ntej cov txheej txheem teem tseg. Saib xyuas INR ze.
Nruab nrab cytochrome P450 3A4 inhibition tuaj yeem cuam tshuam cov metabolism ntawm qee cov tshuaj suav nrog cov kws khomob, calcium channel blockers, benzodiazepines, statins, thiab tshuaj tiv thaiv kab mob yog tias noj ib txhij. Tshawb nrhiav kev sib tham.
Yog tias muaj kev tsis haum tshuaj, tsis txhob siv. Nrhiav kev kho mob rau caj pas hnyav o, ua pa luv, lossis lwm yam tsos mob hnyav.
Ib txwm sib tham ntxivBoswellia Serrata Extractlos yog lwm yam tshuaj ntsuab nrog koj tus kws kho mob ua ntej yog tswj xyuas tus mob mob ntev los yog noj cov tshuaj noj kom muaj kev ceev faj raws li koj tus kheej cov ntaub ntawv kho mob.
Xaus
Nrog nws cov resinous ntau heev 3-5% concentration ntawm boswellic acids muaj zog thiab txhawb botanical tebchaw, purified boswellia serrata cov pos hniav extracts tau rightfully tau txais ib qho chaw nyob rau hauv niaj hnub integrative tshuaj. Kev tshawb nrhiav dav dav rau hauv cov txheej txheem molecular ntawm kev nqis tes ua ua ke nrog ntau qhov zoo ntawm tib neeg kev sim tshuaj txhawb nqa cov ntawv thov Ayurvedic rau boswellia hauv kev tswj kev noj qab haus huv inflammatory teb; txhawb kev sib koom tes ua haujlwm zoo, txav mus los, thiab ncig; txhawb kev noj qab haus huv neurological thiab acuity; tswj kev tiv thaiv kab mob; thiab tejzaum nws tseem tiv thaiv qee hom kab mob thaum noj prophylactically. Tseem qhov no tsuas yog qhov ntxeev ntawm cov dej khov kho zoo thaum nws los txog rau kev kho lub peev xwm ntawm Boswellia serrata.
Kev tshawb fawb tsis tu ncua txuas ntxiv nthuav tawm txoj hauv kev sib txawv no cov boswellic acids cuam tshuam nrog cellular o cascades, cytokine ntau lawm, gene qhia, circulatory dynamics, neural connectivity, thiab tiv thaiv bio-networking thoob plaws hauv lub cev. Raws li peb txoj kev nkag siab ntawm holistic phyto-pharmacology tob zuj zus, yog li peb yuav muaj peev xwm los siv cov xwm txheej nyob hauv pharmacopeia rau kev tiv thaiv thiab kho. Boswellia serrata yog ib qho piv txwv tseem ceeb - hauv paus rau yav thaum ub, tsis tau muab cov lus cog tseg rau yav tom ntej.
Yog tias koj txaus siab rau kev yuav khoomBoswellia Serrata Extract, yog tias koj tab tom nrhiav rau ib tus neeg muag khoom, hu rau Botanical Cube Inc. Yog xav paub ntxiv lossis xa daim ntawv thov, thov hu rau peb ntawmsales@botanicalcube.com. Peb ua kom muaj tseeb, ruaj khov, ntau lawm los ntawm kev siv cov ntaub ntawv pov thawj, cov cuab yeej ua tau zoo tshaj plaws, thiab kev ua haujlwm siab heev hauv kev ua raws li cov qauv zoo thoob ntiaj teb.
Cov ntaub ntawv:
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2. Roy NK, Deka A, Bordoloi M, et al. Boswellia serrata oleogoo resin excerpt alleviates pelvic o thiab mob visceral conceivably los ntawm modulating yooj yim teb thiab cheapening oxidative kev nyuaj siab nyob rau hauv sim ntxias endometriosis nyob rau hauv nas. J Ethnopharmacol. 2020; 252112643. doi10.1016/j.jep.2019.112643.
3. Sengupta K, Krishnaraju AV, Vishal AA, et al. txheeb ze ua tau zoo thiab tolerability ntawm 5- Loxin thiab Aflapin Tawm tsam osteoarthritis ntawm lub hauv caug ob qhov muag tsis pom, randomized, placebo tswj kev tshawb fawb soj ntsuam. Int J MedSci. 2010; 7(6) 366- 377. doi10.7150/ ijms.7.366
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5. Gupta I, Parihar A, Malhotra P, thiab al. cov khoom ntawm Boswellia serrata goo resin nyob rau hauv cov neeg mob uas muaj bronchial hawb pob tshwm sim ntawm ob-qhov muag tsis pom kev, placebo- tswj, 6- lub lis piam kev tshawb fawb soj ntsuam. Eur J MedRes. Xyoo 1998; 3(11)511-514 ib.
6. Ammon HP. Kev hloov pauv ntawm cov kab mob tsis zoo los ntawm Boswellia serrata excerpts thiab boswellic acids. Phytomedicine. 2010; 17(11)862-867 ib. doi10.1016/j.phymed.2010.03.003
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8. Al- Yahya MA, Rafatullah S, Mossa JS, et al. Gastroprotective exertion ntawm boswellia serrata oleogoo resin tiv thaiv ethanol- convinced gastric mucosal lesions nyob rau hauv nas. PhytotherRes. Xyoo 1997; 11(5) 291- 294. doi10.1002/(SICI) 1099- 1573(199708)1153.0. CO; 2- Q
9. Gupta SK, Kataria M, Gupta A, et al. Anti-inflammatory khoom ntawm Boswellia serrata goo resin nyob rau hauv nas nrog collagen-ntseeg mob caj dab. PhytotherRes. 2011; 25(5) 678- 681. doi10.1002/ptr.3323