Nicotinamide mononucleotide (NMN)yog ib qho tseem ceeb ua ntej rau NAD + (Nicotinamide Adenine Dinucleotide), coenzyme uas ua lub luag haujlwm tseem ceeb hauv cov metabolism hauv lub zog, kho DNA, thiab kev noj qab haus huv ntawm tes. Raws li peb muaj hnub nyoog, NAD + qib ib txwm poob qis, ua rau muaj ntau yam muaj hnub nyoog ntsig txog thiab txo qhov tseem ceeb. Los ntawm kev ntxiv nrog NMN, peb tuaj yeem tsim kho NAD + qib, pab tiv thaiv kev laus thiab txhawb kev noj qab haus huv tag nrho. NMN tau tshwm sim los ua ib qho nrov NAD + precursor, tab sis yuav ua li cas piv rau lwm yam NAD + boosters zoo li Nicotinamide Riboside (NR), Nicotinamide (NAM), thiab Tryptophan? Cia wb mus saib ntxiv.
NMN Sib piv li cas rau Lwm NAD + Precursors?
Thaum muab piv rau NMN rau lwm tus NAD + precursors, ntau yam tseem ceeb yuav tsum tau xav txog, xws li bioavailability, kev ua tau zoo, kev nyab xeeb, thiab nqi. Txhua tus neeg ua ntej ua haujlwm los ntawm ntau txoj hauv kev los nce qib NAD +, thiab lawv cov txiaj ntsig tuaj yeem sib txawv nyob ntawm tus neeg thiab cov qauv.
| NAD + Precursor | Bioavailability | Kev ua tau zoo hauv Boosting NAD + | Kev ruaj ntseg Profile | Nqi | Case Study Piv txwv |
|---|---|---|---|---|---|
| NMN | Nruab nrab mus rau siab | Kev nce nrawm hauv NAD + hauv cov ntaub so ntswg | Feem ntau muaj kev nyab xeeb, kev mob me me (mob taub hau, xeev siab) hauv qee kis | Nruab nrab mus rau siab | Ib xyoo 2021 tib neeg sim tau pom tias NMN supplementation nce NAD + qib los ntawm 40% hauv 10 lub lis piam[1]. |
| NR (Nicotinamide Riboside) | Siab | NAD + txhawb nqa zoo, txawm tias kev hloov pauv qeeb dua NMN | Muaj kev nyab xeeb, zoo ib yam li cov kev mob tshwm sim me me tau tshaj tawm raws li NMN | Nruab nrab | Ib txoj kev tshawb fawb luam tawm xyoo 2018 pom tau tias nce 60% hauv NAD + qib tom qab 6 lub lis piam ntawm NR supplementation[2]. |
| NAM (Nicotinamide) | Siab | Nruab Nrab NAD + txhawb nqa, tab sis tuaj yeem cuam tshuam sirtuins (cov protein txuas rau lub neej ntev) ntawm koob tshuaj siab | Muaj kev nyab xeeb ntawm cov koob tshuaj pom zoo, muaj peev xwm tshwm sim ntawm cov koob tshuaj ntau | Tsawg | Ib txoj kev tshawb fawb 2019 pom NAD + qib tsuas yog nce 15% tom qab 8 lub lis piam ntawm NAM supplementation[3]. |
| Tryptophan | Tsawg | Tsawg kawg NAD + ua ntej, xav tau cov kauj ruam hloov dua siab tshiab | Muaj kev nyab xeeb, feem ntau siv rau hauv kev tsim cov protein thiab serotonin ntau lawm | Tsawg | Kev sim xyoo 2020 pom muaj kev hloov pauv tsawg kawg hauv NAD + qib tom qab 12 lub lis piam ntawm Tryptophan supplementation[4]. |
1. Bioavailability
Bioavailability yog hais txog qhov zoo ntawm lub cev absorbs thiab siv lub precursor. NMN muaj qhov nruab nrab mus rau siab bioavailability, nyob ntawm tus qauv tsim thiab kev xa khoom. Liposomal thiab sublingual cov ntaub ntawv ntawm NMN txhim kho nws txoj kev nqus, ua rau nws ua haujlwm sai dua NAD + booster dua li lwm cov precursors xws li NR lossis Tryptophan. NR, ntawm qhov tod tes, muaj bioavailability siab vim nws txoj kev hloov pauv ncaj qha rau hauv NAD + los ntawm txoj hauv kev yooj yim metabolic.
Hauv kev tshawb fawb 2021, cov neeg koom nrog uas tau noj 500 mg ntawm NMN txhua hnub rau 10 lub lis piam pom qhov nce 40% hauv NAD + qib, qhia txog nws cov txiaj ntsig ua ntej. Hauv kev sib piv, cov neeg uas coj NR tau ntsib qhov zoo sib xws hauv NAD +, tab sis nws siv sijhawm 6 lub lis piam kom ncav cuag 60% nce.[1][2].
2. Ua tau zoo hauv Boosting NAD+
NMN paub txog nws lub peev xwm sai thiab muaj txiaj ntsig los txhawb NAD + qib hauv cov ntaub so ntswg, tshwj xeeb hauv daim siab thiab cov leeg hlwb, ua rau nws yog qhov kev xaiv zoo tshaj plaws rau cov uas tab tom nrhiav NAD + txhawb nqa sai. NR kuj txhawb nqa NAD + qib tau zoo tab sis yuav siv sijhawm ntev dua ua li ntawd, raws li pom hauv kev tshawb fawb soj ntsuam. NAM nce NAD + ntau nruab nrab thiab tuaj yeem cuam tshuam kev ua haujlwm ntawm qee cov enzymes, zoo li sirtuins, uas yog qhov tseem ceeb rau kev kho cellular thiab kev ua haujlwm ntev.
Ib txoj kev tshawb fawb 2018 piv NR thiab NMN pom tias NR nce NAD + qib los ntawm 60% tom qab 6 lub lis piam ntxiv, thaum NMN pom tias nce 40% NAD + qib tom qab 10 lub lis piam, txawm hais tias NMN muaj qhov cuam tshuam sai dua hauv cov ntaub so ntswg NAD + qib.[1][2].
3. Kev ruaj ntseg Profile
Txhua NAD + precursors feem ntau suav hais tias muaj kev nyab xeeb rau kev noj tshuaj ntxiv thaum noj hauv cov tshuaj pom zoo. Txawm li cas los xij, kev noj ntau ntawm NAM tuaj yeem cuam tshuam qee cov enzymes uas muaj txiaj ntsig thiab ua rau muaj kev mob tshwm sim me me, xws li xeev siab lossis mob taub hau, uas tau tshaj tawm hauv NMN thiab NR siv.
Hauv xyoo 2019 txoj kev tshawb xyuas NAM, cov kws tshawb fawb pom tias cov neeg koom nrog uas tau noj ntau npaum li cas ntawm NAM tau ntsib cov txiaj ntsig NAD + tsawg dua, vim tias nws cuam tshuam cov haujlwm sirtuin. Qhov no sib piv nrog NMN, uas tsis tau pom qhov cuam tshuam zoo sib xws ntawm cov enzymes ntawm tib koob tshuaj.[3].
4. Tus nqi
Thaum sib piv cov nqi, NMN nyiam tus nqi siab dua NR thiab NAM, feem ntau vim yog cov txheej txheem tsim khoom ntau dua yuav tsum tau ua kom purity thiab ruaj khov. Txawm li cas los xij, muab nws qhov nrawm NAD + txhawb nqa lub peev xwm thiab xav tau kev lag luam muaj zog, ntau tus neeg siv khoom pom tus nqi tsim nyog rau nws cov txiaj ntsig kev noj qab haus huv.
Kev tshuaj xyuas kev lag luam xyoo 2020 tau pom tias NMN cov tshuaj ntxiv nruab nrab yog $ 1.5 ib koob, thaum NR yog kwv yees li $ 1.2 ib koob, ua rau NMN me ntsis kim dua li nws cov neeg sib tw tab sis feem ntau nyiam rau nws txoj kev ua tau zoo sai.[4].
Superior Choice rau NAD + Boosting thiab Longevity
Thaum muab piv NMN nrog rau lwm yam NAD + precursors xws li NR, NAM, thiab Tryptophan, NMN muaj qhov tshwj xeeb zoo, tshwj xeeb tshaj yog nyob rau hauv nws cov kev ua tau zoo thiab ceev hauv kev nce qib NAD +. Nws yog qhov kev xaiv saum toj kawg nkaus rau cov tib neeg uas nrhiav tau sai, txhim khu kev qha rau kev txhawb nqa NAD + qib thiab txhawb nqa lub neej ntev. Raws li cov chaw tsim khoom thiab cov khoom lag luam ntawm NMN raw cov ntaub ntawv, Botanical Cube Inc. tau mob siab rau ua kom tau raws li cov qauv zoo tshaj plaws. Peb NMN tau txheeb xyuas qhov purity, bioavailability, thiab stability, ua rau nws zoo tagnrho rau cov manufacturers ntxiv.
Txawm hais tias koj yog ib lub tuam txhab me lossis cov tsim khoom loj, peb muabNMN hauv bulk, nrog rau kev cai sib xyaw ua kom haum rau koj cov khoom xav tau tshwj xeeb. Yog xav paub ntxiv txog peb cov khoom lossis nug txog koj cov khoom siv raw NMN, thov hu rau peb ntawmsales@botanicalcube.com. Peb txais tos ob qho tib si me me thiab loj xaj, thiab pebKev pabcuam OEMnyob ntawm no los txhawb koj lub hom phiaj kev loj hlob.
Cov ntaub ntawv
1.NMN kev tshawb fawb ntxiv, 2021 (qhov chaw hauv 1st piv kab).
2.NR supplementation study, 2018 (source in 1st comparison row).
3.NAM kawm ntawm NAD + thiab sirtuins, 2019 (qhov chaw hauv 2nd sib piv kab).
4.Kev tsom xam kev ua lag luam ntawm NAD + ua ntej, 2020 (qhov chaw hauv 4th sib piv kab).