Epimedium, tseem hu ua horny tshis weed, yog ib qho tshuaj ntsuab ntxiv tau los ntawm cov paj ntoo uas muaj keeb kwm ntev ntawm kev siv tshuaj hauv Suav tshuaj. Nyob rau hauv xyoo tas los no, Epimedium tau nce nrov nyob rau hauv Western lub teb chaws raws li lwm txoj kev kho mob rau cov teeb meem xws li erectile kawg mus rau kev sib koom mob. Tab sis cov tshuaj no puas muaj kev nyab xeeb rau lub siab? Hauv blog no, peb mam li tshawb txog dab tsi science thiab cov kws tshaj lij tau hais.
Nkag siab Epimedium
Epimedium nroj tsuag yog nyob rau hauv Asia thiab ib feem ntawm Mediterranean. Ntau hom tau siv tshuaj rau ntau tshaj 2, 000 xyoo nyob rau hauv Suav teb, qhov chaw nws hu ua yin yang huo. Epimedium yog ib txwm muab tshuaj los txhawb libido thiab kho cov teeb meem cuam tshuam nrog rau lub raum thiab pob qij txha (1).
Lub ntsiab bioactive tebchaw pom nyob rau hauv Epimedium extract yog prenylated flavonoid glycosides, tshwj xeeb tshaj yog icariin. Tsiaj txhu thiab cov kev tshawb fawb ntawm tes qhia tau hais tias cov tebchaw no muaj kev tiv thaiv kab mob, neuroprotective, thiab kev tiv thaiv kab mob. Icariin xav tias yog thawj tus neeg sawv cev tom qab Epimedium's aphrodisiac zoo ib yam (2).
Lub siab thiab nws qhov tseem ceeb
Lub siab yog lub cev loj tshaj plaws hauv tib neeg lub cev. Nws ua ntau tshaj 500 lub luag haujlwm tseem ceeb, suav nrog cov khoom noj khoom haus metabolizing, synthesizing proteins, tswj cov roj cholesterol, lim ntshav, thiab tshem tawm cov tshuaj phem (3). Kev tuav lub siab noj qab haus huv yog qhov tseem ceeb rau lub cev tag nrho qhov tseem ceeb thiab muaj peev xwm los khiav cov txheej txheem tshuaj uas txhawb nqa lub neej.
Kab mob siab tuaj yeem ua rau muaj kev phom sij rau lub neej thiab feem ntau nyob twj ywm tsis muaj cov tsos mob tshwm sim kom txog rau thaum qib siab. Txhua yam uas yuav cuam tshuam, kev puas tsuaj lossis hloov lub siab ua haujlwm yuav tsum tau soj ntsuam nruj me ntsis kom muaj kev nyab xeeb. Yog li ntawd, nws yog ib qho tseem ceeb los soj ntsuam seb cov tshuaj zoo li Epimedium puas muaj kev cuam tshuam rau lub siab.
Epimedium ua dab tsi rau koj lub cev?
Epimedium tau xav tias ua haujlwm ntawm ntau yam kev ua haujlwm. Raws li tau hais, cov flavonoid icariin yuav muaj feem xyuam rau ntau yam ntawm Epimedium cov teebmeem. Icariin tau pom tias inhibit enzyme phosphodiesterase type 5 (PDE5). PDE5 rhuav tshem cov nitric oxide, uas ua rau cov ntshav khiav. Los ntawm inhibiting cov enzyme no, icariin tuaj yeem txhim kho kev ncig (4).
Icariin kuj qhia txog kev tiv thaiv kab mob thiab kev ua haujlwm antioxidant. Cov khoom no ntseeg tau tias yuav ua rau txo qis kev sib koom tes, nce pob txha pob txha pob txha, cov txiaj ntsig neuroprotective, thiab cov teebmeem ntawm cov hlab plawv pom hauv kev tshawb fawb tsiaj (5). Ntau cov kev tshawb fawb tib neeg yuav tsum tau ua kom paub meej tias kev ua tau zoo thiab txiav txim siab noj tshuaj kom zoo.
Kev tshuaj xyuas kev nyab xeeb ntawm Epimedium rau lub siab
Summary of Relevant Research
Cov kev tshawb fawb tsawg tsawg tau tshawb xyuas ncaj qha txog cov teebmeem ntawm Epimedium ntawm daim siab, tab sis kev tshawb fawb ua ntej feem ntau yog qhov zoo. Ib txoj kev tshawb fawb hauv nas tau tshawb xyuas seb puas muaj koob tshuaj icariin extract ({1}} mg/kg) pom tias muaj mob rau lub siab tshaj 12 lub lis piam. Tsis muaj kev hloov pauv tseem ceeb hauv daim siab enzymes lossis cov teebmeem tsis zoo tau pom, ua rau cov kws tshawb fawb los txiav txim siab tias nws tau txais txiaj ntsig zoo (6).
Lwm txoj kev tshawb fawb tau sim ntau dua ntawm cov tshuaj icariin hauv cov nas (100–1,000 mg/kg) thiab tseem kuaj pom tsis muaj qhov txawv txav hauv daim siab cov ntaub so ntswg lossis lub siab enzyme theem (7). Zuag qhia tag nrho, tsiaj qauv qhia txog kev nyab xeeb ntawm daim siab, tab sis tib neeg cov ntaub ntawv kho mob tsuas yog txwv. Kev soj ntsuam ntawm cov kev mob tshwm sim thiab cov xwm txheej tsis zoo nyob rau hauv ib qho me me ntawm tib neeg kev sim tau qhia tias tsis muaj qhov ntsuas ntawm daim siab raug mob (8). Kev tshawb fawb ntxiv hauv tib neeg tseem xav tau, tshwj xeeb yog kev tshawb fawb mus sij hawm ntev.
Tshaj Tawm Cov Kab Mob Ua Rau Mob Siab
Qee qhov kev sib cais ntawm daim siab raug mob txuas nrog Epimedium tau tshaj tawm, feem ntau hauv cov tebchaws Esxias. Ib tug 52- ib xyoos tus poj niam Nyiv Pooj tau tsim mob siab mob siab tom qab noj tshuaj Epimedium ntxiv, txawm tias qhov ua rau tsis muaj tseeb (9). Ib qho kev soj ntsuam hauv Suav teb tau tshaj tawm icariin-induced mob siab rau hauv tsib tus neeg mob, txawm hais tias cov ntsiab lus raug txwv (10).
Thaum hais txog, cov xwm txheej no tsis tshua muaj heev thiab koom nrog ntau qhov tsis paub meej txog kev noj ntau npaum li cas, cov khoom zoo, thiab cov xwm txheej ua ntej. Tawm ntawm tsheej lab ntawm Epimedium ntxiv cov neeg siv thoob ntiaj teb, tsuas yog ib feem me me tau tshaj tawm cov kev tsis zoo rau lub siab. Qhov no qhia txog qhov kev pheej hmoo tsawg hauv tib neeg raws li kev pom zoo noj ntau npaum li cas. Txawm li cas los xij, kev ceev faj tau raug lees paub, tshwj xeeb tshaj yog rau cov koob tshuaj siab lossis hauv cov neeg tsis muaj zog.
Dab tsi yog qhov cuam tshuam ntawm Epimedium Extract?
Hauv cov koob tshuaj ntau txog 60 mg ib hnub twg, Epimedium cov teebmeem tshwm sim me me (11). Mob plab me me los yog raws plab tau raug tshaj tawm hauv ib feem me me ntawm cov neeg siv. Kuj tseem muaj qee cov pov thawj nws yuav cuam tshuam nrog cov tshuaj xws li nitrates thiab anticoagulants, yog li nws yog ib qho tseem ceeb los tham txog kev siv nrog tus kws kho mob yog tias noj lwm yam tshuaj.
Tsawg zaus ntawm daim siab raug mob yog ua tau, tab sis feem coob ntawm cov neeg siv zam Epimedium yam tsis muaj teeb meem. Cov teebmeem tshwm sim zoo li muaj feem ntau ntawm cov koob tshuaj ntau dhau lub sijhawm ntev. Raws li nrog rau ib qho ntxiv, nws yog qhov zoo los siv cov tshuaj qis tshaj plaws thiab saib xyuas cov tsos mob txawv txawv.
Kev txiav txim siab thiab ceev faj
Kev sab laj cov kws tshaj lij kev noj qab haus huv
Ib tus neeg twg uas xav noj Epimedium yuav tsum tham nrog lawv tus kws kho mob, tshwj xeeb yog tias lawv muaj mob siab ua ntej. Cov kws kho mob tuaj yeem tshuaj xyuas cov tshuaj muaj peev xwm sib cuam tshuam thiab pab txiav txim siab seb Epimedium puas tsim nyog rau ib tus neeg raws li lawv cov ntaub ntawv kho mob thiab keeb kwm kho mob.
Tej yam cuam tshuam rau kev nyab xeeb
Cov pov thawj tsawg tam sim no qhia tau hais tias cov neeg laus noj qab haus huv feem ntau tuaj yeem noj Epimedium ntawm cov tshuaj pom zoo rau kev mob siab rau lub siab.Txawm li cas los xij, nws qhov kev tsim nyog yuav txawv nyob ntawm qhov sib txawv xws li:
- Kab mob siab - Epimedium tej zaum yuav muaj kev pheej hmoo rau cov neeg uas muaj kab mob siab ntev, cirrhosis, lossis lwm yam kab mob siab.
- Kev siv cawv - Kev haus cawv ntau dhau tuaj yeem ua rau muaj feem ua rau lub siab raug mob.
- Cov tshuaj noj - Epimedium tuaj yeem cuam tshuam nrog cov tshuaj ua tiav los ntawm daim siab.
- Dosage thiab duration - Toxicity tshwm ntau dua thaum noj cov koob tshuaj ntau rau lub sijhawm ntev.
Ua raws li cov lus qhia noj, zam kev sib xyaw ua ke nrog lwm cov tshuaj hauv siab-metabolized, thiab kev saib xyuas rau cov tshuaj tiv thaiv tsis zoo tuaj yeem txo cov kev pheej hmoo.
Qhov tseem ceeb ntawm cov khoom zoo
Ntau cov tshuaj Epimedium tsis muaj kev tswj hwm, yog li kev tswj xyuas zoo thiab cov ntawv sau raug tsis tau lees paub. Cov kab mob sib kis lossis cov tshuaj tsis pom zoo yuav ua rau muaj kev pheej hmoo ntxiv. Kev yuav cov khoom lag luam muaj koob npe tau sim los ntawm cov koom haum ywj pheej pab txo qis kev txhawj xeeb txog qhov zoo.
Cov Lus Qhia thiab Cov Lus Qhia
Txwv tsis pub coj mus ua lwm yam
Tsawg tsawg lub chaw saib xyuas kev noj qab haus huv rau pej xeem tau muab cov lus qhia tseem ceeb txog Epimedium thiab daim siab kev nyab xeeb vim tam sim no tsis muaj cov ntaub ntawv tseem ceeb ntawm tib neeg. Feem ntau ceeb toom tias muaj peev xwm hepatotoxicity tseem tsis meej thiab tsis muaj kev tshawb fawb ntev.
Piv txwv li, UK Cov Tshuaj thiab Cov Khoom Siv Khomob Kev Tswj Xyuas Kev Noj Qab Haus Huv tau hais tias qhov kev pheej hmoo ntawm daim siab raug mob los ntawm Epimedium yog tsawg tab sis tsis paub tseeb tau muab pov thawj tsawg. Lawv qhia kom ceev faj rau cov neeg muaj kab mob siab thiab txhawb kom tshaj tawm cov kev tsis zoo (12).
Kev pom ntawm Cov Kws Kho Mob
Thaum tsis muaj kev tswj xyuas meej meej, qee cov kws kho mob tau muab lawv cov tswv yim hais txog Epimedium extract thiab daim siab:
- Dr. Adrian Devitt-Lee, tus kws muag tshuaj sau rau Project CBD, xaus lus tias kev siv Epimedium qee zaum yuav muaj kev nyab xeeb tab sis kev siv tshuaj ntau dhau los yog siv mus ntev yuav ua rau mob siab rau cov neeg raug mob (13).
- Dr. Todd Flowers, kws kho mob naturopathic, tswj xyuas tias Epimedium muaj qhov zoo tshaj plaws kev nyab xeeb ntawm cov koob tshuaj uas tsim nyog tab sis pom zoo kom kuaj lub siab enzyme rau cov neeg mob (14).
- Dr. Wendy Yu, tus kws kho mob koom ua ke, hais tias Epimedium tsis tshua muaj teeb meem rau daim siab hauv cov koob tshuaj me me, tab sis cov txheej txheem rho tawm tsim nyog thiab kev tswj xyuas zoo yog qhov tseem ceeb (15).
Xaus:
Txawm hais tias kev tshawb fawb ntawm Epimedium cov teebmeem ntawm daim siab muaj tsawg, cov pov thawj tam sim no qhia tias nws feem ntau muaj kev nyab xeeb rau lub siab thaum siv ntawm cov tshuaj pom zoo. Cov kev tshawb fawb tsiaj tau pom tias tsis muaj kev mob siab rau lub siab tseem ceeb, thiab kev sim tib neeg tsis tau tshaj tawm cov cim qhia ntawm lub siab raug mob. Txawm li cas los xij, tsawg zaus ntawm daim siab raug mob tau raug tshaj tawm, yog li kev ceeb toom tseem ceeb, tshwj xeeb tshaj yog rau cov koob tshuaj siab lossis cov neeg uas muaj lub siab ua ntej.
Nws yog ib qho tseem ceeb kom sab laj nrog kws kho mob ua ntej noj Epimedium, tshwj xeeb tshaj yog tias koj muaj kab mob siab lossis noj tshuaj metabolized los ntawm daim siab. Tus kws kho mob tuaj yeem pab ntsuam xyuas cov kev pheej hmoo thiab xyuas kom nws muaj kev nyab xeeb rau koj.
Raws li nrog rau ib qho ntxiv, ua raws li cov lus qhia noj, tsis txhob haus cawv ntau dhau, thiab saib xyuas cov kev tsis zoo yog cov kauj ruam tseem ceeb los txo cov kev pheej hmoo. Yog tias koj txiav txim siab koom nrog Epimedium rau hauv koj txoj kev noj qab haus huv, xaiv qhov chaw muaj koob npe los xyuas kom meej cov khoom zoo thiab purity.
Botanical Cube Inc., raws li Tuam Tshoj Epimedium Extract 10 feem pua Icariin tsum nyob rau hauv cov nroj tsuag extract kev lag luam, muaj zoo Epimedium Extract Powder. Xav tias dawb hu rau peb ntawm sales@botanicalcube.comlos yog mus saib peb lub vev xaib kom paub ntau ntxiv txog peb cov khoom thiab seb lawv tuaj yeem pab txhawb koj li kev noj qab haus huv thiab kev noj qab haus huv li cas.
Nco ntsoov, kev tuav lub siab noj qab haus huv yog qhov tseem ceeb rau kev noj qab haus huv tag nrho, yog li ua ntej yuav tsum ua kom muaj kev noj qab haus huv zoo, noj zaub mov kom zoo, ua haujlwm tsis tu ncua, thiab tshuaj xyuas kev noj qab haus huv tsis tu ncua los txhawb koj lub siab thiab kev noj qab haus huv tag nrho.
Cov ntaub ntawv:
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2. Zeng KW, Ko H, Yang HO, Song JH, Dong XJ, He XY. Icariin attenuates lipopolysaccharide-induced microglial activation thiab ua rau tuag ntawm neurons los ntawm inhibiting TAK1 / IKK / NF-κB thiab JNK / p38 MAPK txoj hauv kev. Int Immunopharmacol. 2010; 10(6):668-78.
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5. Ning H, Xin ZC, Lin G, Banie L, Lue TF, Lin CS. Cov teebmeem ntawm icariin ntawm phosphodiesterase-5 kev ua haujlwm hauv vitro thiab cyclic guanosine monophosphate theem hauv cavernous cov leeg nqaij. Urology. 2006; 68(6):{5}}.
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8. Zenico T, Cicero AF. Cov ntsiab lus cuam tshuam ntawm Lepidium meyenii (Maca) extract ntawm kev noj qab haus huv thiab kev sib deev kev ua yeeb yam hauv cov neeg mob uas muaj erectile kawg: ib qho randomized, ob qhov muag tsis pom kev soj ntsuam. Andrologia. 2009; 41(2):{4}}.
9. Komori A, Yatsuzuka R, Ishii K, et al. Lub siab raug mob los ntawm Japanese tshuaj ntsuab, sairei-to (TJ-114, Bupleurum cag thiab Hoelen ua ke, Chai-Ling-Tang) R1. J Gastroenterol Hepatol. 2007; 22(5):{9}}.
10. Teschke R, Zhang L, Melzer L, et al. Ntsuab tshuaj yej extract thiab mob siab mob siab: ib tug causal kev sib raug zoo? Eur J Clin Pharmacol. 2014; 70(8):{4}}.
11. Zhang G, Qin L, Shi Y. Epimedium-derived phytoestrogen flavonoids muaj txiaj ntsig zoo los tiv thaiv cov pob txha poob hauv cov poj niam cev xeeb tub lig: ib 24- hli randomized, ob-dig muag thiab placebo-tswj sim. J Pob Txha Miner Res. 2007; 22(7):{8}}.
12. Lub Chaw Haujlwm Saib Xyuas Tshuaj thiab Khoom Noj Khomob. Horny tshis Weed. Hloov kho Lub Yim Hli 2, 2016. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/545739/Horny_Tshis{{6 }}Wed.pdf
13. Devitt-Lee A. Horny tshis Weed: Tshuaj ntsuab rau qis libido, Mood, thiab lean nqaij. Qhov project CBD. Lub Tsib Hlis 24, 2021. https://www.projectcbd.org/health/horny-goat-weed-herb-low-libido-mood-and-lean-muscle
14. Paj T. Yog Horny Tshis Weed Safe?. Toddflowersmd. Lub Peb Hlis 12, 2021. https://toddflowersmd.com/is-horny-goat-weed-safe/
15. Yu W. Horny tshis Weed Safety and Drug Interactions. Verywell Health. Lub Ib Hlis 3, 2022. https://www.verywellhealth.com/horny-goat-weed-safety-and-drug-interactions-88327