Nicotinamide mononucleotide, feem ntau hu ua NMN, tau txais kev saib xyuas hauv xyoo tas los no rau nws lub luag haujlwm tseem ceeb hauv kev tiv thaiv kev laus thiab kev noj qab haus huv.NMNyog ib qho molecule uas tshwm sim hauv tib neeg lub cev thiab pab nce qib ntawm NAD + (nicotinamide adenine dinucleotide), coenzyme tsim nyog rau ntau yam kev ua haujlwm lom neeg xws li lub zog metabolism, kho DNA, thiab cell ciaj sia. NAD + qib poob qis thaum peb muaj hnub nyoog, thiab qhov kev poob qis no tau txuas nrog ntau yam kab mob uas muaj hnub nyoog thiab kev poob qis hauv kev noj qab haus huv. NMN cov tshuaj ntxiv tau xav tias yuav pab ntxiv NAD + qib, txhawb nqa lub neej ntev, thiab txhim kho kev noj qab haus huv tag nrho.
Txawm li cas los xij, raws li NMN ntxiv kev lag luam loj hlob, ua kom ntseeg tau tias NMN cov khoom lag luam tau dhau los ua qhov tseem ceeb. Tsis yog tag nrho cov tshuaj NMN yog tib yam, thiab kev nkag siab txog qhov ua tau zoo NMN cov khoom lag luam yog qhov tseem ceeb rau cov neeg siv khoom thiab cov chaw tsim khoom.
Dab tsi yog qhov ntsuas qhov tseem ceeb rau NMN tshuaj?
Thaum xaiv lossis tsim cov tshuaj NMN, ntau qhov ntsuas qhov tseem ceeb yuav tsum raug txiav txim siab. Cov ntsuas no tsis tsuas yog ua kom cov khoom siv tau zoo, tab sis kuj muaj kev nyab xeeb. Cov hauv qab no yog cov tseem ceeb tshaj plaws:
1. Purity ntawm NMN
Lub purity ntawm NMN yog ib qho tseem ceeb tshaj plaws ntsuas qhov zoo. High purity ntawm NMN xyuas kom meej tias cov khoom muaj cov khoom xyaw nquag hauv daim ntawv muaj zog tshaj plaws uas tsis muaj cov kab mob los yog cov khoom tsis tsim nyog. NMN cov khoom uas muaj purity ntawm 98% lossis siab dua yog suav tias yog qhov zoo rau kev tsim khoom ntxiv.
Ib xyoo 2020 txoj kev tshawb fawb soj ntsuam ntau yam tshuaj NMN hauv kev ua lag luam pom tias cov khoom siv ntshiab tsawg muaj cov hlau hnyav hnyav thiab lwm yam kab mob uas tuaj yeem ua rau muaj kev phom sij rau kev noj qab haus huv. Ib qho tshwj xeeb NMN cov khoom lag luam nrog purity ntawm 90% tau pom tias muaj 10% ntawm cov khoom siv tsis pom zoo, suav nrog cov lej ntawm cov hlau lead, ua rau nws tsis muaj kev nyab xeeb rau kev siv mus ntev.[1].
| Khoom | Purity (%) | Pom muaj kab mob (mg/kg) |
|---|---|---|
| NMN Brand A | 98.5 | Tsis muaj |
| NMN Brand B | 90 | Lead ({0}}.5 mg/kg) |
| NMN Brand C | 92 | Cadmium ({0}}.3 mg/kg) |
Cov lus no qhia tau hais tias qhov sib piv meej ntawm NMN purity theem thiab muaj cov kab mob phem. Nws qhia tias yog vim li cas siab purity yog ib qho tseem ceeb ntawm cov khoom zoo.
2. Kev ruaj ntseg ntawm NMN
Lwm qhov tseem ceeb qhov ntsuas qhov zoo yog qhov ruaj khov ntawm NMN. NMN yog qhov nkag siab zoo rau ib puag ncig yam xws li kub, lub teeb, thiab av noo. Yog tias tsis tsim khoom thiab ntim khoom kom raug, NMN tuaj yeem ua rau tsis zoo thiab poob nws cov txiaj ntsig ua ntej mus txog cov neeg siv khoom.
Ib txoj kev tshawb fawb 2022 tau soj ntsuam qhov degradation tus nqi ntawm NMN cov tshuaj ntxiv nyob rau hauv cov xwm txheej sib txawv. Cov txiaj ntsig tau pom tias NMN khaws cia rau hauv lub thawv tsis ntim khoom ntawm chav tsev kub poob 40% ntawm nws lub zog nyob rau hauv rau lub hlis, thaum NMN khaws cia rau hauv lub thawv kaw, noo noo-pov thawj khaws ntau dua 95% ntawm nws lub zog nyob rau tib lub sijhawm.[2].
| Kev cia khoom | Potency Retained (%) tom qab 6 lub hlis |
|---|---|
| Chav ntsuas kub, tsis kaw | 60% |
| Chav ntsuas kub, kaw | 95% |
| Txias, kaw | 98% |
Cov ntaub ntawv no qhia txog qhov tseem ceeb npaum li cas kom khaws cia thiab ntim khoom kom ruaj ntseg NMN.
3. Bioavailability
Bioavailability hais txog qhov twg thiab qhov nrawm ntawm lub cev nqus thiab siv NMN. Cov tshuaj NMN zoo yuav tsum tau tsim los ua kom muaj txiaj ntsig zoo tshaj plaws. Qee cov khoom NMN tau txhim kho nrog cov khoom xyaw xws li liposomal thev naus laus zis lossis lwm cov khoom siv bio-txhim kho kom zoo dua qub.
Kev sim tshuaj 2021 piv rau bioavailability ntawm standard NMN capsules rau liposomal NMN. Cov txiaj ntsig tau pom tias cov neeg koom nrog kev noj cov liposomal version muaj 50% siab dua NAD + qib tom qab 4 lub lis piam dua li cov neeg siv daim ntawv tshuaj ntsiav.[3].
| Hom Tshuaj Ntxiv | Nce hauv NAD + Qib (%) tom qab 4 lub lis piam |
|---|---|
| Standard NMN | 30% |
| Liposomal NMN | 45% |
Qhov no qhia txog qhov cuam tshuam ntawm kev tsim ntawm NMN qhov ua tau zoo hauv kev txhawb nqa NAD + qib hauv lub cev.
4. Kev xeem thiab ntawv pov thawj thib peb
Kev ntsuam xyuas thib peb yog ib qho tseem ceeb ntawm cov cim zoo uas muab kev pom tseeb thiab kev ntseeg siab rau qhov zoo ntawm cov khoom ntxiv. Cov tuam txhab muaj npe nrov NMN yuav tsum muab Daim Ntawv Pov Thawj Kev Ntsuam Xyuas (COA) los ntawm lub chaw soj nstuam ywj pheej los xyuas kom meej meej purity, ruaj khov, thiab tsis muaj cov kab mob xws li cov hlau hnyav, tshuaj tua kab, lossis kab mob microbial.
Xyoo 2023, ib lub koom haum soj ntsuam ywj pheej pom tias 25% ntawm NMN tshuaj ntsuam xyuas tsis tau raws li lawv daim ntawv thov rau purity lossis potency. Txawm li cas los xij, cov khoom lag luam uas tau lees paub los ntawm lwm tus tau pom tias ua tau raws li cov lus pom zoo lossis tshaj lawv daim ntawv thov[4].
| Certification Status | % ntawm Cov Khoom Sib Ntsib Cov Ntawv Thov |
|---|---|
| Certified (Tib neeg thib peb) | 100% |
| Tsis-Certified | 75% |
Cov ntaub ntawv no qhia txog qhov tseem ceeb ntawm kev xaiv cov khoom lag luam nrog cov ntawv pov thawj thib peb rau kev lav zoo.
5. Kev noj tshuaj kom raug
Kev noj tshuaj kom raug yog qhov tseem ceeb los xyuas kom meej tias cov tshuaj NMN ua haujlwm raws li qhov xav tau. Cov tshuaj ntxiv yuav tsum muaj qhov tseeb ntawm NMN teev nyob rau ntawm daim ntawv lo. Kev hloov ntau npaum li cas tuaj yeem ua rau cov txiaj ntsig tsis zoo lossis txawm tias muaj peev xwm tshwm sim yog tias koob tshuaj ntau dhau.
Kev tshuaj xyuas xyoo 2022 ntawm 10 NMN cov npe tshuaj ntxiv tau qhia tias peb lub npe muaj tsawg dua 80% ntawm cov tshuaj tau teev tseg. Ib hom tshuaj muaj tsuas yog 60% ntawm cov tshuaj NMN tau teev tseg thiab tsis tshua muaj txiaj ntsig zoo dua li tshaj tawm[5].
| Hom | Labeled Dose (mg) | Qhov koob tshuaj tiag tiag (mg) |
|---|---|---|
| NMN Brand X | 500 | 300 |
| NMN Brand Y | 300 | 240 |
| NMN Brand Z | 600 | 600 |
Qhov no ntxiv txhawb qhov yuav tsum tau muaj kev sim nruj kom ntseeg tau tias qhov tseeb npaum li cas.
Koj Trusted NMN Raw Material Supplier
Raws li cov chaw tsim khoom thiab cov khoom lag luam ntawm NMN raw cov ntaub ntawv, Botanical Cube Inc. tau tsom mus rau kev ua tau raws li tag nrho cov ntsiab lus tseem ceeb saum toj no. Peb muab NMN nrog ntau dua 98% purity, sim rau kev ruaj ntseg, bioavailability, thiab cov kab mob, tag nrho cov pov thawj los ntawm cov neeg thib peb xeem. Peb NMN muaj nyob rau hauv ntau, thiab peb kuj muajKev pabcuam OEM, kev cai sib xyaw kom tau raws li peb cov neeg siv khoom xav tau tshwj xeeb.
Seb koj yog ib tug me me startup los yog lojNMNcov chaw tsim khoom ntxiv, peb txais tos txhua qhov kev txiav txim thiab tos ntsoov kom loj hlob nrog peb cov neeg siv khoom. Yog xav paub ntxiv lossis tham txog koj cov khoom xav tau, thov hu rau peb ntawmsales@botanicalcube.com.
Cov ntaub ntawv
1.Study on NMN ntxiv purity thiab contaminants, 2020 (qhov chaw hauv kab lus thib 3).
2.Degradation kawm txog NMN kev ruaj ntseg nyob rau hauv txawv cia tej yam kev mob, 2022 (qhov chaw nyob rau hauv nqe lus 6).
3.Clinical trial on bioavailability of liposomal NMN vs standard NMN, 2021 (source in 9th kab lus).
4.Kev ntsuam xyuas thib peb ntawm NMN cov tshuaj ntxiv, 2023 (qhov chaw nyob rau hauv nqe lus 12).
5.Kev tshuaj xyuas ntawm NMN ntxiv qhov tseeb, 2022 (qhov chaw hauv nqe 14).