Icariin yog ib qho tshwm sim tshwm sim uas muaj ntau yam kev kho mob. Pom feem ntau hauv cov nroj tsuag los ntawm lub Epimediumnplooj, icariin tau dhau los ua qhov nrov ntxiv vim nws lub peev xwm los txhim kho kev sib deev kev noj qab haus huv, kev ua haujlwm ntawm lub cev, thiab kev txawj ntse. Kab lus no yuav tshawb txog kev tshawb fawb tom qab icariin, cov khoom noj khoom haus sab saum toj, thiab nws yuav pab tau koj li cas.
Icariin yog dab tsi?
Icariin yog ib qho flavonoid glycoside thiab qhov tseem ceeb tshaj plaws nyob rau hauv horny tshis nroj (Epimedium spp.). Nws yog hu ua synthetically li prenyl icaritin los yog 3, 7-dihydroxy-4'- methoxy-8-(3-methyl-2-butenyl)- flavone.
Icariin suav hais tias yog ib qho prenylated flavonoid, txhais tau tias nws muaj ib pawg isoprenoid ntxiv uas tso cai rau nws nkag mus rau txhua lub hlwb sai dua thiab siv cov kev cuam tshuam hauv lub cev. Qhov no muab icariin tshiab pharmacological ce sib piv nrog cov flavonoids sib txawv.
Cov txiaj ntsig zoo ntawm icariin muaj xws li:
- Aphrodisiac zoo
- Kev kho erectile kawg
- Txhim khu kev ua kis las
- Txhim kho kev paub txog kev ua haujlwm
- Anti-inflammatory teebmeem
- Cov qib testosterone ntau ntxiv
- Vasodilation thiab txhim kho kev ncig
Cov teebmeem no raug ntaus nqi rau ntau lub tswv yim, suav nrog nce nitric oxide ntau lawm, txo cov haujlwm PDE5, txhawb kev loj hlob ntawm cov paj hlwb synthesis, thiab tswj cov qib tshuaj hormones. Cia peb tshawb nrhiav cov khoom noj khoom haus saum toj kawg nkaus ntawm qhov sib xyaw zoo nkauj no.
Horny tshis Weed: Thawj Icariin Source
Cov chav kawm Epimedium muaj ob peb lub kaum ob hom herbaceous blossoming nroj tsuag hauv zos rau Tuam Tshoj, Nyiv, thiab ntau daim ntawm Asia. Cov tsiaj sib txawv muaj keeb kwm ntev hauv cov tshuaj suav tshuaj rau kev kho mob xws li qaug zog, mob pob qij txha, mob siab, thiab qaug zog.
Ntawm cov bioactive mixs pom nyob rau hauv Epimedium cais, icariin yog cov feem ntau plentiful thiab pharmacologically muaj zog. Cov ntsiab lus ntawm Icariin sib txawv los ntawm hom:
- E. sagittatum: 1.6-2.6% icariin
- E. brevicornu: 2.5-5% icariin
- E. koreanum: mus txog 15% icariin
Yog li ntawd, E. brevicornu thiab E. koreanum muab qee qhov chaw muaj zog tshaj plaws ntawm icariin hauv qhov xwm txheej. Standardized Epimedium extracts feem ntau muaj 10-60% icariin los ntawm qhov hnyav.
Cov khoom noj tseem ceeb ntawm Epimedium nroj tsuag muaj xws li:
- Cov nplooj nyoos thiab stems: Kev lig kev cai siv tshuaj yej los yog kua zaub.
- Concentrated extracts: Muaj nyob rau hauv capsules, tinctures, hmoov.
- Herbal blends: Ua ke nrog lwm yam tshuaj ntsuab thiab superfoods.
Thaum xaiv ib qho Epimedium ntxiv rau icariin cov ntsiab lus, tshawb xyuas cov qauv kev rho tawm thiab hom nrog qib siab dua li E. koreanum.
Tshaj Horny tshis Weed: Lwm qhov chaw Icariin
Thaum Epimedium hom yog nyob deb ntawm qhov chaw nplua nuj tshaj plaws, lwm cov nroj tsuag muaj cov kab ntawm icariin ib yam nkaus:
Rye (Secale cereale) - Rye pollen muaj kwv yees li 0 3-0.5% icariin. Tsuas yog paj ntoos, tsis yog cereal rye nplej, muab icariin.
Grapevines (Vitis vinifera) - Vine stems thiab nplooj muaj icariin. Cov tawv nqaij liab liab kuj muaj cov tshuaj sib xyaw ua ke ampelopsin.
Jujube txiv hmab txiv ntoo (Ziziphus jujube) - Jujube, ib txwm siv hauv Suav tshuaj, muab cov ntsiab lus icariin.
Passionflower (Passiflora spp.) - Qee hom zoo li P. incarnata kuj tseem muaj qib qis heev.
Txawm li cas los xij, txij li cov ntsiab lus icariin yog marginal los ntawm cov peev txheej no, Epimedium extracts tseem yog qhov kev xaiv noj zaub mov nkaus xwb.
Cov Khoom Noj Zoo Tshaj Plaws hauv Icariin
Rau cov neeg uas xav kom icariin kom tsawg, cov khoom noj uas siab tshaj plaws hauv cov tshuaj no suav nrog:
1. Horny tshis weed extract: nce txog 60% icariin los ntawm qhov hnyav.
2. Raw Epimedium nplooj: 1-5% icariin nyob ntawm hom.
3. Cov qauv tshuaj ntsuab nrog Epimedium: Nws txawv raws li cov qauv.
4. Rye pollen extract: Mus txog 0.5% icariin.
5. Grapevine rho tawm: Tsawg feem pua ntawm nplooj thiab stems.
6. Jujube txiv hmab txiv ntoo: Tsis pom qab muaj pes tsawg leeg.
Muab qhov siab bioavailability thiab concentrations, standardized Epimedium extracts yog nyob deb ntawm qhov zoo tshaj plaws noj icariin qhov chaw. Rau cov txiaj ntsig ntxiv, kev sib txuas Epimedium nrog cov khoom noj khoom haus zoo li citrus, berries, nplooj ntsuab, thiab cov rog noj qab haus huv tuaj yeem txhim kho icariin cov teebmeem.
Icariin, Nitric Oxide, thiab Vascular Function
Ib lub tswv yim tom qab icariin cov kev kho mob cuam tshuam nrog nce nitric oxide (NO) ntau lawm. Nitric oxide yog lub teeb liab molecule uas so cov hlab ntsha, ua kom cov hlab ntsha thiab cov ntshav ntws. Qhov no muab ntau yam txiaj ntsig:
- Txhim kho kev xa cov pa oxygen thiab cov as-ham rau cov ntaub so ntswg
- Txhim kho lub cev kev ua haujlwm thiab kev ua siab ntev
- Kho erectile kawg los ntawm kev txhawb nqa penile ntshav ntws
- Txo cov ntshav siab
Icariin zoo li nce NO ntau lawm los ntawm ntau txoj hauv kev. Qhov no suav nrog kev txhawb nqa kev qhia ntawm nitric oxide synthase (NOS) enzymes thiab tiv thaiv tsis muaj kev puas tsuaj los ntawm inhibiting PDE5 enzymes.
Los ntawm kev txhim kho NO-mediated vasodilation, icariin tuaj yeem txhim kho ntau yam tsis muaj feem cuam tshuam txog kev noj qab haus huv ntawm cov hlab plawv. Ntau qhov kev sim tib neeg tseem xav tau los lees paub qhov zoo tshaj plaws thiab kev ua tau zoo, txawm li cas los xij.
Lub peev xwm ntawm Icariin Powder
Kev tshawb fawb thaum ntxov qhia tau hais tias icariin tuaj yeem muaj peev xwm kho tau los ntawm ntau lub tshuab lom neeg:
- Txhim kho testosterone thiab tswj cov tshuaj hormones kev loj hlob
- Txhawb nqa neurite kev loj hlob thiab cov teebmeem neuroprotective
-Suppressing inflammatory cytokines
- Exhibiting anticancer zog
- Tiv thaiv oxidative neuronal puas
Cov tshuaj tua kab mob antioxidant, tiv thaiv kab mob, thiab kev tswj hwm ntawm tes ntawm icariin yuav ua rau muaj ntau yam txiaj ntsig. Txawm li cas los xij, feem ntau cov kev tshawb fawb tseem nyob rau lub sijhawm no.
Thaum pom tias muaj kev nyab xeeb, cov kev mob tshwm sim ntawm kev noj tshuaj icariin siab tuaj yeem suav nrog kiv taub hau, xeev siab, thiab mob plab me me. Icariin kuj tseem cuam tshuam nrog cov tshuaj rau erectile kawg thiab ntshav siab.
Nco ntsoov sab laj nrog koj tus kws kho mob ua ntej pib noj tshuaj ntxiv, tshwj xeeb tshaj yog tias tau txais kev kho mob lossis noj cov tshuaj noj. Zuag qhia tag nrho, icariin qhia tau hais tias cog lus tias yog cov khoom noj muaj txiaj ntsig zoo rau kev txhim kho txiv neej txoj kev noj qab haus huv, kev paub, kev ua siab ntev, thiab kev loj hlob.
cov txiaj ntsig ntxiv
1. Pob txha noj qab haus huv
- Invigorates osteoblast sib cais thiab pob txha pob txha
- inhibits pob txha resorption los ntawm osteoclasts
- tuaj yeem pab nrog Forestalling osteoporosis thiab hnub nyoog txog cov pob txha tsis zoo
2. Mob hlwb
- Tiv thaiv neurons thiab txhawb kev loj hlob ntawm neurite los ntawm NGF
- Txo cov beta amyloid plaques thiab tau proteins
- Tej zaum yuav pab kho Alzheimer's thiab dementia
3. Kev cai tiv thaiv kab mob
- Qhia txo qhov cuam tshuam los ntawm kev cuam tshuam NF-kB txoj hauv kev
- Tej zaum yuav pab daws cov teeb meem provocative zoo li rheumatoid pob qij txha
- Pab txav ntawm ib txwm executioner hlwb thiab macrophages
4. Metabolic Health
- Txhim kho insulin rhiab heev thiab cov metabolism hauv qabzib
- Txo cov roj (cholesterol) thiab triglycerides
- tuaj yeem pab kho mob metabolic syndrome thiab ntshav qab zib
5. Kev noj qab haus huv ntawm daim tawv nqaij
- Activates collagen synthesis thiab inhibits MMP enzymes
- Pab kho UV puas thiab photoaging ntawm daim tawv nqaij
- Txo cov tsos ntawm wrinkles thiab txhim kho elasticity
Feem ntau, cov txiaj ntsig zoo xav tau koob tshuaj tsawg kawg yog 20-60 mg / kg lub cev hnyav hauv cov qauv tsiaj. Tib neeg txoj kev tshawb fawb tseem xav tau kom paub meej txog cov txiaj ntsig thiab kev noj tshuaj zoo. Icariin cov txheej txheem kho mob yuav tshwm sim los ntawm nws cov tshuaj tiv thaiv antioxidant thiab kev cuam tshuam nrog cov txheej txheem lom neeg tseem ceeb.
Tsim kom muaj txiaj ntsig Icariin Supplementation Strategies
Txhawm rau kom tau txais txiaj ntsig zoo tshaj plaws ntawm icariin supplementation, qee cov tswv yim zoo suav nrog:
- Siv cov txheej txheem Epimedium rho tawm kom pom lub zog zoo
- Noj icariin hmoov koob tshuaj ntawm 100-200 mg txhua hnub
- Muab icariin nrog cov khoom noj uas muaj citrulline kom nce qib nitric oxide
- Lub voj voog icariin - 5 hnub rau, 2 hnub so kom tsis txhob kam ua siab ntev
- Noj cov tshuaj icariin rau 2-3 lub hlis kom tau txais txiaj ntsig zoo
- Pair icariin nrog kev tawm dag zog maj mam rau kev ncig thiab cov txiaj ntsig neuroprotective
- Tsis txhob noj icariin ob peb teev ua ntej yuav mus pw vim muaj peev xwm stimulation
Cov txheej txheem ntxiv kom zoo tuaj yeem pab txhim kho bioavailability thaum txo cov kev mob tshwm sim. Kev sab laj tus kws kho mob uas paub zoo tuaj yeem pab kho icariin kom tsawg thiab txhim kho rau koj tus kheej lub hom phiaj kev noj qab haus huv.
Yav tom ntej Outlook rau Icariin Kev Tshawb Fawb
Raws li kev tshawb fawb ntawm icariin txuas ntxiv mus, qee thaj chaw cov kws tshawb fawb tab tom tshawb nrhiav suav nrog:
- Kev cuam tshuam rau cov qog nqaij hlav qog nqaij hlav xws li qog nqaij hlav prostate thiab zes qe menyuam
- Cov txiaj ntsig zoo rau kev paub tsis meej xws li dementia, ADHD thiab kev ntxhov siab
- Cov ntawv thov rau kev txhawb nqa lub neej ntev thiab kev laus noj qab haus huv
- Kev kho mob plab zom mov zoo li IBS thiab Crohn's
- Kho cov teebmeem ntawm kev noj qab haus huv mitochondrial thiab cellular zog
- Txoj kev xa tshuaj los txhim kho bioavailability
Cov kev ua ub no ntau yam ntawm icariin tau lees tias nws cov khoom siv tshuaj yuav txuas ntxiv tsis pom hauv cov kev tshawb fawb yav tom ntej. Kev paub txog icariin tag nrho cov peev txheej kho tau tuaj yeem muab kev nyab xeeb, kev hloov pauv ntuj rau kev kho mob ntau yam.
Hauv cov ntsiab lus, icariin yog ib qho kev cog lus prenylated flavonoid compound nrog ntau yam txiaj ntsig kev noj qab haus huv. Cov chaw nplua nuj xws li Bulk Epimedium Extract 40% Icariin extracts muab cov khoom noj yooj yim ntxiv. Kev noj tshuaj kom raug, kev caij tsheb kauj vab, thiab kev sib tsoo tuaj yeem pab ua kom icariin cov teebmeem lom neeg. Raws li kev tshawb fawb txuas ntxiv, qhib icariin lub peev xwm kho mob tag nrho tuaj yeem muab lwm txoj hauv kev los txhim kho kev noj qab haus huv thiab kev loj hlob.
Standardized Epimedium extracts tseem yog cov concentrated thiab txhim khu kev qha ntawm icariin. Cov extracts no tuaj yeem tau txais los ntawm cov kws tshaj lij xws li Botanical Cube Inc., lub npe nrov Tuam Tshoj Epimedium Extract 10% Icariin tsum. Yog xav paub ntxiv los yog tso ib qho kev txiav txim, thov hu rau peb ntawmsales@botanicalcube.com.
Cov ntaub ntawv:
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2. Ma, H., He, X., Yang, Y., Li, M., Hao, D., & Jia, Z. (2011). Lub genus Epimedium: kev tshuaj xyuas ethnopharmacological thiab phytochemical. Phau ntawv Journal of ethnopharmacology, 134(3), 519-541.
3. Shindel, AW, Xin, ZC, Lin, G., Fandel, TM, Huang, YC, Banie, L., ... & Lue, TF (2010). Erectogenic thiab neurotrophic teebmeem ntawm icariin, purified extract ntawm horny tshis nroj (Epimedium spp.) hauv vitro thiab hauv vivo. Phau ntawv Journal of Sexual Medicine, 7(4pt1), 1518-1528.
4. Stanislavov, R., & Nikolova, V. (2003). Kev kho erectile kawg nrog pycnogenol thiab L-arginine. Phau ntawv Journal of Sexual and Reproductive Medicine, 1(3), 207-213.
Xin, ZC, Kim, EK, Lin, CS, Liu, WJ, Tian, L., Yuan, YM, ... & Lue, TF (2003). Cov teebmeem ntawm icariin ntawm cGMP-tshwj xeeb PDE5 thiab cAMP tshwj xeeb PDE4 cov dej num. Asian Journal of andrology, 5(1), 15-18.
5. Zhang, ZB, & Yang, QT (2006). Testosterone mimetic zog ntawm icariin. Asian Journal of andrology, 8(5), 601-605.
6. Zou, P., Xia, Y., Ji, Z., Chen, W., Ding, G., Yao, W., ... & Wang, S. (2016). Icariin: muaj peev xwm osteoinductive compound rau pob txha cov ntaub so ntswg engineering. Tissue Engineering Part A, 22(19-20), 1148-1157.