Ecdysterone yog dab tsi?
Ecdysterone, txwv tsis pub hu ua beta-ecdysterone lossis 20-hydroxyecdysone. Nws muaj qhov chaw nrog kev sib sau ntawm cov tshuaj hu ua ecdysteroids, uas yog qhov tseem ceeb taug qab hauv kab thiab qee yam nroj tsuag. Ecdysterone tau txais kev saib xyuas rau nws cov txiaj ntsig kev noj qab haus huv thiab nws txoj kev sib raug zoo nrogCyanotis arachnoides extract.
Cyanotis arachnoides, feem ntau hu ua "spiderwort plant," yog hom nroj tsuag uas muaj cov qib siab ntawm ecdysterone hauv nws cov hauv paus hniav. Cov extract tau los ntawm cov nroj tsuag no feem ntau yog tus qauv kom muaj qhov tshwj xeeb ntawm ecdysterone. Qhov no extract tau ua nrov raws li kev noj haus ntxiv vim nws cov purported anabolic, adaptogenic, thiab kev ua tau zoo-txhim kho cov khoom.
Kev txhais thiab qhov chaw
Ecdysterone, tseem hu ua 20-Hydroxyecdysone los yog 20E, yog phytosteroid - ib qho tshuaj steroid uas ib txwm tshwm sim hauv cov nroj tsuag [1]. Nws suav hais tias yog ib qho khoom noj khoom haus tshiab uas tau muab rho tawm los ntawm cov tshuaj ntsuab.
Ecdysterone tau pom thawj zaug hauv kab thiab tau txais nws lub npe los ntawm "ecdysis", txheej txheem ntawm molting. Nws pab tswj cov kab metamorphosis thiab kev loj hlob [2].
Nws tseem pom muaj nyob hauv ntau hom nroj tsuag, suav nrog spinach, quinoa, thiab qee yam tshuaj ntsuab. Feem ntau cov khoom siv botanical siv rau kev tsim khoom ntxiv yog Cyanotis arachnoidea thiab Cyanotis vaga nroj tsuag nyob hauv Is Nrias teb thiab Tuam Tshoj [3].
Cov hauv paus hniav thiab saum nruab ntug ntawm cov nroj tsuag no muaj cov qib siab ntawm ecdysterone thiab yog siv los rho tawm thiab ntxuav ecdysterone rau kev lag luam.
Chemical Structure thiab Properties
Chemically, 20 hydroxy ecdysterone yog cais raws li phytoecdysteroid - lub ntsiab lus ntawm cov nroj tsuag ecdysteroid compound. Ecdysteroids yog cov tshuaj steroid uas tswj cov moulting thiab metamorphosis hauv arthropods [4].
Cov qauv tseem ceeb ntawm ecdysterone muaj plaub fused hydrocarbon rings, zoo ib yam li cov roj cholesterol. Tab sis ecdysterone kuj muaj ketone thiab hydroxyl pawg uas tso cai rau nws faib ua phytosteroid [5].
Tsis zoo li anabolic steroids muab los ntawm testosterone, ecdysterone tsis muaj cov qauv tshuaj "steroid-like" . Txawm li cas los xij, nws muaj qee qhov zoo sib xws uas ua rau nws cov teebmeem lom neeg.
Hais txog cov khoom, beta ecdysterone raug suav hais tias muaj kev nyab xeeb ntawm cov koob tshuaj pom zoo. Tab sis qhov zoo thiab purity yuav tsum raug txheeb xyuas, vim cov ntaub ntawv ntawm kev nyab xeeb yog txwv [6].
Ecdysterone ua dab tsi rau lub cev?
Txawm hais tias kev tshawb fawb tseem tab tom tshwm sim, cov kev tshawb fawb qhia tias ecdysterone hmoov yuav muaj txiaj ntsig zoo xws li:
- Ua kom muaj protein ntau ntxiv - Hauv kev tshawb fawb ntawm tes thiab tsiaj txhu, ecdysterone ua kom pom cov khoom siv anabolic los ntawm kev ua kom cov leeg nqaij protein synthesis [7]. Qhov no yog txuas nrog nws lub peev xwm los ua kom muaj nitric oxide ntau lawm uas txhim kho cov leeg hlwb [8].
- Txhawb nqa ATP cov ntsiab lus - Ecdysterone tuaj yeem ua rau cov khoom tsim tawm ntawm ATP, lub zog tseem ceeb hauv cov hlwb. Qhov no yuav txhais tau ntau lub zog ntawm tes [9].
- Txo kev qaug zog - Qee qhov kev tshawb fawb qhia tias ecdysterone tuaj yeem txo cov cim ntawm kev qaug zog thiab ua kom rov zoo tom qab qoj ib ce [10].
- Modulating cov tshuaj hormones - Ecdysterone tuaj yeem pab sib npaug cov tshuaj hormones xws li estradiol thiab testosterone uas tswj cov leeg loj hlob thiab cov metabolism [11].
- Txo cov rog rog - Tsiaj cov kev tshawb fawb ceeb toom ecdysterone tuaj yeem txo qis cov rog hauv lub cev thaum nce cov nqaij ntshiv [12]. Qhov no tej zaum yuav yog vim muaj kev hloov pauv hauv cov noob caj noob ces.
Txawm li cas los xij, kev tshawb fawb tam sim no tsuas yog siv rau kev tshawb fawb ntawm tes thiab cov qauv tsiaj. Kev tshawb nrhiav ntxiv yog xav tau kom paub tseeb tias cov teebmeem hauv tib neeg. Tham nrog koj tus kws kho mob ua ntej siv cov tshuaj ecdysterone.
Ecdysterone puas yog Steroid?
Thaum muab faib ua phytosteroid, ecdysterone tsis suav tias yog qhov tseeb "anabolic steroid" zoo li testosterone lossis hluavtaws derivatives. Qhov no yog vim tsis zoo li cov tshuaj steroids, nws tsis ua rau androgen receptors uas cuam tshuam rau kev loj hlob ntawm cov txiv neej poj niam txiv neej [13].
Txawm li cas los xij, beta ecdysterone cuam tshuam nrog cov tshuaj estrogen receptors uas yuav ua rau nws cuam tshuam rau cov leeg nce, lub zog metabolism, thiab cov tshuaj hormones sib npaug [14]. Yog li txawm hais tias tsis yog classic steroidal androgen, nws muaj steroid zoo li kev ua haujlwm.
Puas yog Ecdysterone zoo dua li Steroids?
Ecdysterone yog qee zaum ua lag luam raws li "natural thiab nyab xeeb" lwm txoj rau anabolic steroids. Thiab cov kev tshawb fawb thaum ntxov hauv cov tsiaj thiab cov hlwb qhia tias nws tuaj yeem pab txhawb cov leeg nqaij thiab lub zog.
Txawm li cas los xij, thov tias ecdysterone muaj zog lossis zoo dua li steroids tsis muaj pov thawj txaus rau tib neeg. Xav tau kev tshawb fawb ntxiv ua ntej yuav muaj kev sib piv.
Lub ntsiab kom zoo dua ecdysterone tam sim no muaj tshaj steroids yog nws qhov kev pheej hmoo tsawg dua. Thaum siv kom tsim nyog, phytosterols zoo li ecdysterone tsis cuam tshuam nrog cov kev mob hnyav hnyav ntawm anabolic steroids [15].
Tab sis rau ob qho tib si kev ua tau zoo thiab cov kev pheej hmoo ntawm kev phiv, cov tshuaj steroid tseem yuav muaj zog dua li ecdysterone raws li cov ntaub ntawv tam sim no. Yuav tsum tau tshawb nrhiav ntau ntxiv.
Kev nyab xeeb, noj, thiab kev txiav txim siab
Cov tshuaj Ecdysterone feem ntau tau txais txiaj ntsig zoo los ntawm cov neeg laus noj qab haus huv ntawm cov koob tshuaj pom zoo xws li 200-500 mg ib hnub. Kev nyab xeeb mus sij hawm ntev dhau los 6 lub hlis tsis tau tsim. Tej yam tshwm sim tej zaum yuav muaj xws li mob plab hnyuv me [16].
Cov neeg uas muaj mob ua ntej yuav tsum sab laj nrog kws kho mob ua ntej siv. 20 Hydroxy Ecdysterone kuj yuav tsum tau zam los ntawm cov poj niam cev xeeb tub lossis cov poj niam laus vim tias cov ntaub ntawv tsis txaus ntseeg.
Muab nws qhov muaj koob meej tshwm sim hauv lub voj voog qoj ib ce, kev tshawb fawb loj ntawm tib neeg ntawm ecdysterone tau lees paub. Tab sis kom deb li deb, nws qhia tau hais tias kev cog lus raws li ib qho kev ua tau zoo-txhim kho ntxiv nrog rau cov kev mob tshwm sim qis dua piv rau anabolic steroids.
Hauv kev xaus, ecdysterone yog phytosteroid compound pom nyob rau hauv kab thiab qee yam nroj tsuag. Nws muaj cov txiaj ntsig kev noj qab haus huv thiab feem ntau muab rho tawm los ntawm Cyanotis arachnoides cog. Txawm hais tias kev tshawb fawb tseem tsis tu ncua, cov kev tshawb fawb qhia tias ecdysterone hmoov yuav muaj cov nyhuv anabolic thiab kev ua tau zoo, xws li nce protein synthesis, txhawb cov ntsiab lus ATP, txo qis qaug zog, thiab hloov cov tshuaj hormones. Txawm li cas los xij, kev tshawb fawb ntxiv yog xav tau kom paub tseeb tias cov teebmeem no hauv tib neeg. Tsis zoo li cov tshuaj anabolic steroids, ecdysterone tsis ua rau androgen receptors tab sis cuam tshuam nrog estrogen receptors. Thaum nws tau ua lag luam raws li lub ntuj thiab kev nyab xeeb lwm txoj rau steroids, nws tsis muaj pov thawj txaus los txhawb kev lees paub tias muaj zog lossis zoo dua li cov tshuaj steroids. Cov tshuaj Ecdysterone feem ntau tau txais txiaj ntsig zoo ntawm cov koob tshuaj pom zoo, tab sis kev nyab xeeb mus ntev thiab cov kev mob tshwm sim yuav tsum tau tshawb xyuas ntxiv.
Botanical Cube Inc. tau tshwj xeeb hauv kev cog qoob loo rau ntau xyoo, thiab raws li 20 Hydroxy Ecdysterone Powder tus neeg muag khoom, peb tuaj yeem muab koj cov khoom zoo tshaj plaws ntawm tus nqi pheej yig tshaj. Txhawm rau tso qhov kev txiav txim rau Lag luam wholesale 20 Hydroxy Ecdysterone Powder lossis nug txog peb lwm cov khoom, thov hu rau peb ntawmsales@botanicalcube.com.
Cov ntaub ntawv:
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10. Azizov AP. Cov teebmeem ntawm eleutherococcus, elton, leuzea, thiab ecdysterone ntawm lub cev ua haujlwm muaj peev xwm ntawm tib neeg [hauv Lavxias] Mezhdunarodnyĭ Biologicheskiĭ Kongress, Sessiia Teeb meem Biologicheskoĭ Aktivnosti Khimicheskikh Soedineniĭ. Moscow, 1981 Abstracts 2nd; 256.
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13. Dinan L, Lafont R. Cov teebmeem thiab kev siv ntawm arthropod steroid hormones (ecdysteroids) hauv cov tsiaj txhu. J Endocrinol. 2006; 191(1):{4}}. doi: 10.1677/joe.1.06859
14. Gorelick-Feldman J, Cohick W, Raskin I. Ecdysteroids elicit sai Ca2 ntxiv flux ua rau Akt activation thiab nce protein synthesis nyob rau hauv cov leeg pob txha. Cov tshuaj steroids. 2010; 75(10):632-637. doi: 10.1016/j.steroids.2010.03.008
15. Ost M, Tamourzadeh Sangari M, Costa D, et al. Kev nyab xeeb, pharmacokinetics, thiab cov metabolism hauv qhov ncauj 20-hydroxyecdysone hauv cov txiv neej noj qab haus huv: qhib-daim ntawv lo rau theem kuv tshuaj-tso-escalation. AAP J. 2021;23(4):76.
16. Simakin SYa. Kev sib xyaw ua ke ntawm Ecdisten thiab cov khoom 'Bodrost' thaum lub sij hawm Kev cob qhia hauv Cyclical Hom Kev Ua Si. Scientific Sports Bulletin. 1988; (2:39–45).